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professional thesis
Potencijali i izazovi izrade magistralnih pripravaka za pedijatrijsku populaciju
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2022. urn:nbn:hr:163:881104
Liščić, Jelica
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmaceutical technology

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Liščić, J. (2022). Potencijali i izazovi izrade magistralnih pripravaka za pedijatrijsku populaciju (Professional thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:881104

Liščić, Jelica. "Potencijali i izazovi izrade magistralnih pripravaka za pedijatrijsku populaciju." Professional thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2022. https://urn.nsk.hr/urn:nbn:hr:163:881104

Liščić, Jelica. "Potencijali i izazovi izrade magistralnih pripravaka za pedijatrijsku populaciju." Professional thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2022. https://urn.nsk.hr/urn:nbn:hr:163:881104

Liščić, J. (2022). 'Potencijali i izazovi izrade magistralnih pripravaka za pedijatrijsku populaciju', Professional thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 23 December 2024, https://urn.nsk.hr/urn:nbn:hr:163:881104

Liščić J. Potencijali i izazovi izrade magistralnih pripravaka za pedijatrijsku populaciju [Professional thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2022 [cited 2024 December 23] Available at: https://urn.nsk.hr/urn:nbn:hr:163:881104

J. Liščić, "Potencijali i izazovi izrade magistralnih pripravaka za pedijatrijsku populaciju", Professional thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:163:881104

Metadata
TitlePotencijali i izazovi izrade magistralnih pripravaka za pedijatrijsku populaciju
AuthorJelica Liščić
MentorJelena Filipović-Grčić (mentor)
Committee memberŽeljka Vanić (predsjednik povjerenstva)
Committee memberJelena Filipović-Grčić (član povjerenstva)
Committee memberMaja Lusina Kregar (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmaceutical technology)
Zagreb
Defense date and country2022-11-23, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Magistralni pripravci su od velikog značaja u učinkovitoj personaliziranoj terapiji. Izrađuju se ukoliko se liječenje ne može provesti s odobrenim komercijalno dostupnim lijekom (gotovi lijek). Razlozi za to mogu biti brojni, a najčešće je to prilagodba doze zbog toga što gotovi lijek nije dostupan u adekvatnoj dozi s obzirom na dob i stanje bolesnika, potom prilagodba formulacije u slučaju bolesnika alergičnih ili osjetljivih na pojedine pomoćne tvari gotovog lijeka, bolesnika na enteralnoj prehrani te bolesnika koji pate od teške disfagije. Potreba za izradom magistralnih pripravaka posebno je izražena u pedijatriji. S obzirom da se radi o posebno osjetljivoj skupini bolesnika, cilj ovog rada je, kroz primjere iz ljekarničke prakse, ukazati na potencijale i izazove izrade učinkovitih, sigurnih i stabilnih pedijatrijskih magistralnih pripravaka u obliku suspenzija, podijeljenih prašaka i kapsula.
Abstract (english)
Magistral formulations are of great importance for effective personalized therapy. They are often prepared and used when treatment cannot be given with a commercially available drug, because the drug is not available at an adequate dose (depending on the age of the patient), or when the drug formulation is not suitable for use in patients requiring dose adjustment, or when the patient is sensitive to certain excipients in the commercial drug, as well as in patients who are fed enterally nutrition, and in patients suffering from severe dysphagia. The need for the use of magistral formulations is particularly pronounced in the pediatric population. Since children are particularly sensitive group of patients, the aim of this study is to present examples from pharmacy practice to highlight the opportunities and challenges in the manufacture of pediatric magistral formulations in the form of suspensions, divided powders and capsules, and to highlight their shortcomings in terms of manufacture and quality.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:881104
Study programmeTitle: Drug development
Study programme type: university
Study level: postgraduate specialist
Academic / professional title: sveučilišni magistar/sveučilišna magistra razvoja lijekova (sveučilišni magistar/sveučilišna magistra razvoja lijekova)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-01-09 15:54:37