prikaz prve stranice dokumenta Primjena ciklodekstrina u razvoju farmaceutskih oblika za primjenu antitumorskih lijekova
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Professional paper - Review paper
Primjena ciklodekstrina u razvoju farmaceutskih oblika za primjenu antitumorskih lijekova
Farmaceutski glasnik, 79 (2023), 1-2; 1-20. urn:nbn:hr:163:385656
Nikolin, Martina; Jug, Mario

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Nikolin, M. & Jug, M. (2023). Primjena ciklodekstrina u razvoju farmaceutskih oblika za primjenu antitumorskih lijekova. Farmaceutski glasnik, 79. (1-2), 1-20. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:385656

Nikolin, Martina and Mario Jug. "Primjena ciklodekstrina u razvoju farmaceutskih oblika za primjenu antitumorskih lijekova." Farmaceutski glasnik, vol. 79, no. 1-2, 2023, pp. 1-20. https://urn.nsk.hr/urn:nbn:hr:163:385656

Nikolin, Martina and Mario Jug. "Primjena ciklodekstrina u razvoju farmaceutskih oblika za primjenu antitumorskih lijekova." Farmaceutski glasnik 79, no. 1-2 (2023): 1-20. https://urn.nsk.hr/urn:nbn:hr:163:385656

Nikolin, M. and Jug, M. (2023) 'Primjena ciklodekstrina u razvoju farmaceutskih oblika za primjenu antitumorskih lijekova', Farmaceutski glasnik, 79(1-2), pp. 1-20. Available at: https://urn.nsk.hr/urn:nbn:hr:163:385656 (Accessed 22 November 2024)

Nikolin M, Jug M. Primjena ciklodekstrina u razvoju farmaceutskih oblika za primjenu antitumorskih lijekova. Farmaceutski glasnik [Internet]. 2023 [cited 2024 November 22];79(1-2):1-20. Available at: https://urn.nsk.hr/urn:nbn:hr:163:385656

M. Nikolin and M. Jug, "Primjena ciklodekstrina u razvoju farmaceutskih oblika za primjenu antitumorskih lijekova", Farmaceutski glasnik, vol. 79, no. 1-2, pp. 1-20, 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:385656. [Accessed: 22 November 2024]

Metadata
Title (croatian)Primjena ciklodekstrina u razvoju farmaceutskih oblika za primjenu antitumorskih lijekova
AuthorMartina Nikolin
AuthorMario Jug
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmaceutical technology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract (english)
Cyclodextrins (CDs) are excipients able to form inclusion complexes with sterically compatible lipophilic endogenous molecules and drugs, increasing their solubility and chemical stability. Enhanced biocompatibility and the potential to form nanostructures give CDs an advantage over other commercially available excipients. CDs appear as attractive carriers for antitumor drugs, which often show limited aqueous solubility and chemical stability. Therefore, CD may provide the development of new dosage forms and delivery systems of antitumor drugs with improved bioavailability, reduced toxicity and enhanced therapeutical efficiency. In addition, the interactions of CDs with endogenous molecules may act synergistically with antitumor drugs in cancer treatment. Further functionalization of CDs by attaching the ligands specific for receptors typical for tumour cells may provide active tumor targeting of the included cytostatic drugs, additionally enhancing the effectiveness and safety of cancer therapy.
Keywords (croatian)
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review - domestic
Publication versionPublished version
Journal titleFarmaceutski glasnik
Numberingvol. 79, no. 1-2, pp. 1-20
p-ISSN0014-8202
URN:NBNurn:nbn:hr:163:385656
Publication2023
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-03-14 14:08:17