prikaz prve stranice dokumenta HPLC analiza fenolnih kiselina i flavonoidnih aglikona u biljnim vrstama: Betula pendula, Salvia officinalis i Vaccinium myrtillus
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master's thesis
HPLC analiza fenolnih kiselina i flavonoidnih aglikona u biljnim vrstama: Betula pendula, Salvia officinalis i Vaccinium myrtillus
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2016. urn:nbn:hr:163:705253
Šoštarić, Nina
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmacognosy

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

Cite this document

Šoštarić, N. (2016). HPLC analiza fenolnih kiselina i flavonoidnih aglikona u biljnim vrstama: Betula pendula, Salvia officinalis i Vaccinium myrtillus (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:705253

Šoštarić, Nina. "HPLC analiza fenolnih kiselina i flavonoidnih aglikona u biljnim vrstama: Betula pendula, Salvia officinalis i Vaccinium myrtillus." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2016. https://urn.nsk.hr/urn:nbn:hr:163:705253

Šoštarić, Nina. "HPLC analiza fenolnih kiselina i flavonoidnih aglikona u biljnim vrstama: Betula pendula, Salvia officinalis i Vaccinium myrtillus." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2016. https://urn.nsk.hr/urn:nbn:hr:163:705253

Šoštarić, N. (2016). 'HPLC analiza fenolnih kiselina i flavonoidnih aglikona u biljnim vrstama: Betula pendula, Salvia officinalis i Vaccinium myrtillus', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 25 November 2024, https://urn.nsk.hr/urn:nbn:hr:163:705253

Šoštarić N. HPLC analiza fenolnih kiselina i flavonoidnih aglikona u biljnim vrstama: Betula pendula, Salvia officinalis i Vaccinium myrtillus [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2016 [cited 2024 November 25] Available at: https://urn.nsk.hr/urn:nbn:hr:163:705253

N. Šoštarić, "HPLC analiza fenolnih kiselina i flavonoidnih aglikona u biljnim vrstama: Betula pendula, Salvia officinalis i Vaccinium myrtillus", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:163:705253

Metadata
TitleHPLC analiza fenolnih kiselina i flavonoidnih aglikona u biljnim vrstama: Betula pendula, Salvia officinalis i Vaccinium myrtillus
Title (english)HPLC analysis of phenolic acids and flavonoid aglycones in Betula pendula, Salvia officinalis and Vaccinium myrtillus
AuthorNina Šoštarić
MentorMarijana Zovko Končić (mentor)
Committee memberMarijana Zovko Končić (predsjednik povjerenstva)
Committee memberSuzana Inić (član povjerenstva)
Committee memberMaja Ortner Hadžiabdić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmacognosy)
Zagreb
Defense date and country2016-04-25, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
U ovom radu korištena je tekućinska kromatografija visoke djelotvornosti (HPLC) za kvalitativnu i kvantitativnu analizu fenolnih kiselina i flavonoidnih aglikona u tri biljne vrste: Betula pendula, Salvia officinalis i Vaccinium myrtillus koje se koriste u narodnoj medicini za liječenje ili ublažavanje tegoba šećerne bolesti. Detekcija ispitivanih fenolnih kiselina i flavonoidnih aglikona izvršena je pomoću DAD detektora. U ispitivanim biljnim vrstama pronađene su brojne fenolne kiseline i flavonoidi poput ružmarinske i klorogenske kiseline (list kadulje, list borovnice), protokatehuične kiseline (hidrolizirani ekstrakti lista breze i lista borovnice), kavene kiseline (hidrolizirani ekstrakti lista kadulje i lista borovnice), luteolina (list kadulje) i derivata kvercetina (list breze, list borovnice, list kadulje). Prisutnost navedenih fenolnih kiselina i flavonoidnih aglikona djelomično opravdava primjenu ovih biljnih vrsta u terapiji šećerne bolesti, ali pošto je većina studija provedena in vitro ili na animalnim modelima, da bi se njihova učinkovitost potvrdila potrebno je provesti detaljne kliničke studije.
Abstract (english)
In this study, HPLC was used for qualitative and quantitative analysis of phenolic acids and flavonoid aglycones in Betula pendula, Salvia officinalis and Vaccinium myrtillus, which are used in folk medicine for the treatment or alleviation of symptoms of diabetes. Detection of tested phenolic acids and flavonoids was performed with DAD-detector. Numerous phenolic acids and flavonoids were found in these plant species, such as rosmarinic and chlorogenic acid (sage leaf, blueberry leaf), protocatechuic acid (hydrolyzed extracts of birch leaf and blueberry leaf), caffeic acid (hydrolyzed extracts of sage leaf and blueberry leaf), luteolin (sage leaf) and quercetin derivatives (birch leaf, blueberry leaf, sage leaf). The presence of said phenolic acids and flavonoid aglycones partly justifies the application of these plant species in the treatment of diabetes, but since most studies were conducted in vitro or in animal models, to confirm their effectiveness it is necessary to carry out detailed clinical studies.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:705253
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2016-06-07 15:23:16