Tomato pomace is a waste material from the processing of tomatoes and consists of the skin, seeds and remains of the pulp. Previous research has confirmed the presence of phenolic compounds with high antioxidant activity that enable the valorization of tomato pomace for the production of nutraceuticals, i.e. compounds with added value while also solving the problem of bio-waste disposal. Biologically active components of tomato pomace, primarily carotenoids and phenolic compounds exhibit anti-inflammatory, antimutagenic and anticancer effects. This diploma thesis investigates the influence of different types of drying (drying in a thermostat at 70°C and freeze drying) on the content of bioactive components with antioxidant activity and compares the proportion of said components in different parts of tomato pomace (whole pomace, skin and seeds). Total phenols were determined using the Folin-Ciocalteu method, radical binding capacity was determined using the TEAC method, and antioxidant efficiency was measured using the ORAC method. The obtained results show that the drying process significantly affects the content of polyphenols, i.e. drying tomato pomace in a thermostat at 70°C is a better option for preserving the antioxidant potential compared to drying tomato pomace by freezing. A correlation between the content of polyphenols and antioxidant potential has been proven. It was also confirmed that the skin of the tomato contains a significantly higher amount of polyphenolic compounds with antioxidant activity than the seeds of the tomato. The results can contribute to existing knowledge about tomato pomace as a valuable secondary raw material for its better utilization in the form of obtaining bioactive components with antioxidant activity.