Climate changes are becoming more pronounced and have a significant effect on mold growth and mycotoxin production. An increase in temperature and concentration of carbon dioxide along with changes in the amount of rainfall lead to a change in the biodiversity of the microbiome and greater contamination of foodstuffs. Colonized crops represent a great damage to the agricultural sector, but also a threat to human health. 90 grain samples from warehouses in March 2022, collected in northern, central and eastern Croatia, were analyzed. The research showed the highest concentration of mold on corn samples from northern Croatia on both used media (2.8 x 106 CFU/g on DG-18 agar and 5.3 x 106 CFU/g on DRBC agar). Superior growth was shown by the mold genera Penicillium with an average frequency above 50%. Next in order of frequency were molds of the genera Fusarium, whose growth dominated on the corn samples. The growth of molds of the genera Cladosporium, as well as yeasts, was also present to a greater extent. Although aflatoxins are considered the greatest threat to human health, in the present study, the growth of Aspergilli section Flavi was recorded with a maximum frequency of only 30% on corn samples from eastern Croatia (DG-18). The impairment of grain quality is most visible on corn samples that are considered even unacceptable for feeding animals. Taking care of the drying and storage conditions as well as the prevention of wounding by insects, are critical points in the life cycle of grains. Maintaining the quality and safety of grains can be achieved by ensuring Good Agricultural Practices (GAP) and using the Hazard Analysis and Critical Control Point (HAACP). The impact on industrial gas emissions can be of crucial importance for the prevention of mold growth and the preservation of human health, especially taking into account the expected changes in climate conditions.