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Scientific paper - Original scientific paper
Diterpenes and phenolic compounds from Salvia brachyodon Vandas
Croatica Chemica Acta, 96 (2023), 1; 45-50. https://doi.org/10.5562/cca3994
Bucar, Franz; Mitić, Božena; Hruševar, Dario; Kunert, Olaf; Binder, Kerstin; Ochensberger, Sandra; Friščić, Maja; Jurić, Sandra; Marić, Tihana; Maleš, Željan

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Bucar, F., Mitić, B., Hruševar, D., Kunert, O., Binder, K., Ochensberger, S. ... Maleš, Ž. (2023). Diterpenes and phenolic compounds from Salvia brachyodon Vandas. Croatica Chemica Acta, 96. (1), 45-50. doi: 10.5562/cca3994

Bucar, Franz, et al. "Diterpenes and phenolic compounds from Salvia brachyodon Vandas." Croatica Chemica Acta, vol. 96, no. 1, 2023, pp. 45-50. https://doi.org/10.5562/cca3994

Bucar, Franz, Božena Mitić, Dario Hruševar, Olaf Kunert, Kerstin Binder, Sandra Ochensberger, Maja Friščić, Sandra Jurić, Tihana Marić and Željan Maleš. "Diterpenes and phenolic compounds from Salvia brachyodon Vandas." Croatica Chemica Acta 96, no. 1 (2023): 45-50. https://doi.org/10.5562/cca3994

Bucar, F., et al. (2023) 'Diterpenes and phenolic compounds from Salvia brachyodon Vandas', Croatica Chemica Acta, 96(1), pp. 45-50. doi: 10.5562/cca3994

Bucar F, Mitić B, Hruševar D, Kunert O, Binder K, Ochensberger S, and sur.. Diterpenes and phenolic compounds from Salvia brachyodon Vandas. Croatica Chemica Acta [Internet]. 2023 [cited 2024 June 06];96(1):45-50. doi: 10.5562/cca3994

F. Bucar, et al., "Diterpenes and phenolic compounds from Salvia brachyodon Vandas", Croatica Chemica Acta, vol. 96, no. 1, pp. 45-50, 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:915726. [Accessed: 06 June 2024]

Metadata
Title (english)Diterpenes and phenolic compounds from Salvia brachyodon Vandas
AuthorFranz Bucar https://orcid.org/0000-0002-7417-616X
AuthorBožena Mitić
AuthorDario Hruševar
AuthorOlaf Kunert
AuthorKerstin Binder
AuthorSandra Ochensberger
AuthorMaja Friščić
AuthorSandra Jurić
AuthorTihana Marić
AuthorŽeljan Maleš
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmaceutical botany)
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of organic chemistry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract (english)
Salvia brachyodon, the short-tooth sage, is one of the rarest plant species and endemic in the Adriatic area of the Balkan Peninsula. As aside from its essential oil, only limited information on its phytochemical composition is known, a more detailed study of the leaves was undertaken. From its leaves two diterpenes, agastanol (2), and a new natural compound 1, i.e., 3-methyl-4-methylen-11,12,14-trihydroxy-8,11,13-abietatrien-7-one, were isolated and identified by NMR spectroscopy and mass spectrometry. In addition, caffeic acid, isoquercitrin, luteolin 7-O-glucoside and rosmarinic acid were identfied by comparison with reference compounds. The fraction containg the diterpenes as well as the isolated compound 1 showed significant antimycobacterial activity against Mycobacterium smegmatis. The diterpenes of S. brachyodon represent promising antimycobacterial substances for further evaluation. Due to the endangered nature of the plant, the wide use of S. brachyodon and its bioactive compounds could be achieved by growing the plants in culture.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCroatica Chemica Acta
Numberingvol. 96, no. 1, pp. 45-50
p-ISSN0011-1643
e-ISSN1334-417X
DOIhttps://doi.org/10.5562/cca3994
URN:NBNurn:nbn:hr:163:915726
Publication2023
Document URLhttps://hrcak.srce.hr/305850
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-01-26 12:59:16