During the cultivation and industrial processing of tomatoes, large amounts of waste consisting of peel, seeds and pulp remains are generated. This waste is rich in bioactive compounds such as carotenoids (especially lycopene and beta carotene), polyphenols and pectins that show a number of positive effects on human health and can therefore be used as nutraceuticals and/or natural additives in the pharmaceutical or food industry to improve organoleptic properties and food quality. Antioxidant properties, anti-inflammatory action and chemoprevention are the most important biological effects of polyphenols and carotenoids, with beta-carotene also possessing provitamin A activity. The activity of pectin is associated with positive effects on health of digestive system and prevention of atherosclerosis and obesity Therefore, the demand for these compounds is constantly increasing. The development and optimization of sustainable processes for the extraction of polyphenols, carotenoids and pectin from tomato pomace would reduce the cost and ecological footprint of tomato production, as well as the aforementioned bioactive components. The most researched extraction techniques in this regard are conventional extraction with hot dilute acid for pectin, while for the extraction of polyphenols and carotenoids, green extraction techniques such as microwave-assisted extraction and ultrasound-assisted extraction (which are characterized by higher yields using non-toxic solvents) are most often used. The introduction and optimization of mentioned processes at the industrial level and the simplification of the legal regulations related to nutraceuticals and new food obtained from secondary raw materials would result in significant economic and environmental benefits and significantly contribute to the implementation of the principles of the circular economy in the sector of food production and nutritional supplements.