Objective: The aim of this research was to investigate the type and frequency of side effects caused by antipsychotics, which influence the attitude towards pharmacotherapy in schizophrenic patients. Furthermore, the specific aim was to investigate the frequency of reporting suspected adverse drug reactions in these groups of patients. Subjects and methods: The research was approved by the Ethics Committee of the Vrapče Psychiatry Clinic, and it was organized as a cross-sectional study. Respondents included in the research were surveyed in the premises of the Vrapče Psychiatry Clinic, Institute for Female Psychotic Disorders in the period from May to October 2022. Inclusive criteria for respondents are female sex, outpatient treatment of patients, legal age and a confirmed diagnosis of schizophrenia. Results: A total of 109 patients who visited the Department for Female Psychotic Disorders of the Vrapče Psychiatry Clinic during the period under investigation participated in the study and gave their informed consent to participate in the study. The majority of respondents were between 50 and 60 years old, did not have a partner and were not employed. As many as 43.1% of respondents experienced a side effect of antipsychotics, but only one patient reported the suspected side effect to the competent authority. Conclusion: The results of this study show a slightly more negative attitude towards antipsychotic pharmacotherapy in the population which experienced side effect, but show significant ignorance and a lack of practice in reporting suspected side effects of antipsychotics. Because of the above, it can be concluded that there is a need for education of both patients and healthcare professionals about pharmacovigilance.