prikaz prve stranice dokumenta Priprema i karakterizacija vezikularnog fosfolipidnog gela
Embargo period 2025-09-28
master's thesis
Priprema i karakterizacija vezikularnog fosfolipidnog gela
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. urn:nbn:hr:163:728052
Crnković, Maja
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmaceutical technology

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

Cite this document

Crnković, M. (2024). Priprema i karakterizacija vezikularnog fosfolipidnog gela (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:728052

Crnković, Maja. "Priprema i karakterizacija vezikularnog fosfolipidnog gela." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. https://urn.nsk.hr/urn:nbn:hr:163:728052

Crnković, Maja. "Priprema i karakterizacija vezikularnog fosfolipidnog gela." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. https://urn.nsk.hr/urn:nbn:hr:163:728052

Crnković, M. (2024). 'Priprema i karakterizacija vezikularnog fosfolipidnog gela', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 28 December 2024, https://urn.nsk.hr/urn:nbn:hr:163:728052

Crnković M. Priprema i karakterizacija vezikularnog fosfolipidnog gela [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2024 [cited 2024 December 28] Available at: https://urn.nsk.hr/urn:nbn:hr:163:728052

M. Crnković, "Priprema i karakterizacija vezikularnog fosfolipidnog gela", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:163:728052

Metadata
TitlePriprema i karakterizacija vezikularnog fosfolipidnog gela
Title (english)Preparation and characterization of vesicular phospholipid gel
AuthorMaja Crnković
MentorŽeljka Vanić (mentor)
Committee memberŽeljka Vanić (predsjednik povjerenstva)
Committee memberZora Rukavina (član povjerenstva)
Committee memberLovorka Vujić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmaceutical technology)
Zagreb
Defense date and country2024-03-28, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Svrha ovoga rada bila je pripraviti i okarakterizirati polučvrstu formulaciju liposoma iznimno visoke koncenteracije fosfolipida (vezikularni fosfolipidni gel, VFG). Za pripravu je korišten sojin fosfatidilkolin i hidrofilna djelatna tvar. Primjenom visokotlačnog homogenizatora pripravljen je VFG male veličine vezikula i relativno homogene distribucije veličina. Uklapanje hidrofilne djelatne tvari u unutarnju vodenu fazu bilo je visoko u usporedbi s klasičnim metodama priprave liposoma. Izmjerena teksturna svojstva VFG-a pokazuju odgovarajuću čvrstoću i razmazivost prikladnu za dermalnu primjenu.
Abstract (english)
The aim of this study was to prepare and characterize a semi-solid formulation of liposomes with an extremely high concentration of phospholipids, i.e., vesicular phospholipid gel (VPG). Soybean phosphatidylcholine and a hydrophilic model drug were used for the preparation of VPG. Using a high-pressure homogenizer, VPG with a small size of vesicles and a relatively homogeneous size distribution was prepared. Incorporation of the hydrophilic drug into the internal aqueous phase of VPG was high compared to classical methods of liposome preparation. Texture analysis of VPG showed adequate hardness and spreadability suitable for dermal application.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:728052
Study programmeTitle: Pharmacy - integrated undergraduate and graduate - university study
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: sveučilišni magistar farmacije (sveučilišni magistar farmacije)
Type of resourceText
File originBorn digital
Access conditionsEmbargoed access
Embargo expiration date: 2025-09-28
Terms of useLicence In copyright icon
Created on2024-06-13 11:50:49