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master's thesis
Farmakoterapijski pristup liječenju sindroma iritabilnog crijeva
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. urn:nbn:hr:163:372645
Raguž, Petra
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmacology

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Raguž, P. (2024). Farmakoterapijski pristup liječenju sindroma iritabilnog crijeva (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:372645

Raguž, Petra. "Farmakoterapijski pristup liječenju sindroma iritabilnog crijeva." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. https://urn.nsk.hr/urn:nbn:hr:163:372645

Raguž, Petra. "Farmakoterapijski pristup liječenju sindroma iritabilnog crijeva." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. https://urn.nsk.hr/urn:nbn:hr:163:372645

Raguž, P. (2024). 'Farmakoterapijski pristup liječenju sindroma iritabilnog crijeva', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 06 October 2024, https://urn.nsk.hr/urn:nbn:hr:163:372645

Raguž P. Farmakoterapijski pristup liječenju sindroma iritabilnog crijeva [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2024 [cited 2024 October 06] Available at: https://urn.nsk.hr/urn:nbn:hr:163:372645

P. Raguž, "Farmakoterapijski pristup liječenju sindroma iritabilnog crijeva", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:163:372645

Metadata
TitleFarmakoterapijski pristup liječenju sindroma iritabilnog crijeva
Title (english)Pharmacotherapeutic approach to the treatment of irritable bowel syndrome
AuthorPetra Raguž
MentorPetra Turčić (mentor)
Committee memberPetra Turčić (predsjednik povjerenstva)
Committee memberLidija Bach-Rojecky (član povjerenstva)
Committee memberLaura Nižić Nodilo (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmacology)
Zagreb
Defense date and country2024-06-05, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Sindrom iritabilnog crijeva je kompleksna gastrointestinalna bolest i najčešći funkcionalni poremećaj crijeva. Bolest se manifestira različitim simptomima uključujući promjenu u broju i obliku stolica, bolovima u trbuhu, nadutosti i ponekada simptomima izvan gastrointestinalnog sustava. Etiopatogeneza bolesti je multifaktorijalna i uključuje različite genetske, mikrobiološke, imunološke, hormonalne i psihološke čimbenike. Dijagnoza SIC-a se postavlja isključivanjem drugih organskih bolesti i praćenjem Rimskih kriterija IV. Upravljanje SIC-om uključuje različite terapijske pristupe, farmakološke i nefarmakološke. Farmakološki pristupi obuhvaćaju laksative, antidijaroike, spazmolitike, antidepresive i ponekad antibiotike. Nefarmakološki pristupi podrazumijevaju prilagodbu prehrambenih navika, korištenje određenih dodataka prehrani i probiotika, redovitu tjelovježbu i psihoterapiju. Važno je istaknuti individualizirani pristup liječenju koji je ključan kod SIC-a, jer se simptomi bolesti i odgovor na terapiju razlikuju između pacijenata. Potrebna su daljnja istraživanja kako bi se bolje razumjeli mehanizmi ove bolesti i razvili učinkovitiji terapijski pristupi i podigla kvaliteta života bolesnika koji pate od sindroma iritabilnog crijeva.
Abstract (english)
Irritable bowel syndrome (IBS) is a complex gastrointestinal disorder and the most common functional bowel disorder. The disease manifests with various symptoms including changes in bowel habits, abdominal pain, bloating, and sometimes extra-intestinal symptoms. The etiopathogenesis of the disease is multifactorial and includes various genetic, microbiological, immunological, hormonal, and psychological factors. The diagnosis of IBS is established by excluding other organic diseases and following the Rome IV criteria. Management of IBS involves various therapeutic approaches, both pharmacological and non-pharmacological. Pharmacological approaches include laxatives, anti-diarrheal agents, spasmolytics, antidepressants, and sometimes antibiotics. Non- pharmacological approaches include dietary modifications, the use of specific dietary supplements and probiotics, regular exercise, and psychotherapy. It is important to emphasize the individualized approach to treatment, which is crucial in IBS, as symptoms and response to therapy vary among patients. Further research is needed to better understand the mechanisms of this disease and to develop more effective therapeutic approaches to improve the quality of life of patients suffering from irritable bowel syndrome.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:372645
Study programmeTitle: Pharmacy - integrated undergraduate and graduate - university study
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: sveučilišni magistar farmacije (sveučilišni magistar farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-09-23 13:37:03