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master's thesis
Terapijski pristupi u liječenju djece s poremećajima iz spektra autizma
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. urn:nbn:hr:163:564441
Topić, Marinka
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmacology

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Topić, M. (2024). Terapijski pristupi u liječenju djece s poremećajima iz spektra autizma (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:564441

Topić, Marinka. "Terapijski pristupi u liječenju djece s poremećajima iz spektra autizma." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. https://urn.nsk.hr/urn:nbn:hr:163:564441

Topić, Marinka. "Terapijski pristupi u liječenju djece s poremećajima iz spektra autizma." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. https://urn.nsk.hr/urn:nbn:hr:163:564441

Topić, M. (2024). 'Terapijski pristupi u liječenju djece s poremećajima iz spektra autizma', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 06 October 2024, https://urn.nsk.hr/urn:nbn:hr:163:564441

Topić M. Terapijski pristupi u liječenju djece s poremećajima iz spektra autizma [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2024 [cited 2024 October 06] Available at: https://urn.nsk.hr/urn:nbn:hr:163:564441

M. Topić, "Terapijski pristupi u liječenju djece s poremećajima iz spektra autizma", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:163:564441

Metadata
TitleTerapijski pristupi u liječenju djece s poremećajima iz spektra autizma
Title (english)Therapeutic approaches in treating children with autism spectrum disorder
AuthorMarinka Topić
MentorLidija Bach-Rojecky (mentor)
Committee memberLidija Bach-Rojecky (predsjednik povjerenstva)
Committee memberPetra Turčić (član povjerenstva)
Committee memberMiranda Sertić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmacology)
Zagreb
Defense date and country2024-07-23, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Poremećaji iz spektra autizma su pervazivni razvojni poremećaji karakterizirani nepravilnom socijalnom interakcijom i komunikacijiom te prisutnošću ponavljajućih i stereotipnih ponašanja i interesa. Točan uzrok nastanka autizma još uvijek nije poznat, smatra se da je autizam kompleksni poremećaj koji je rezultat međudjelovanja okolišnih čimbenika i genetskih faktora. Autizam se često manifestira uz velik broj pridruženih simptoma kao što su anksioznost, agresija, nepažnja, hiperaktivnost, problemi sa spavanjem te gastrointestinalni problemi. Iako ne postoji specifična terapija dostupna za uklanjanje osnovnih simptoma bolesti, koriste se različiti lijekovi iz brojnih farmakoterapijskih skupina kako bi se ublažili pridruženi simptomi (atipični antipsihotici za razdražljivost i impulzivnost, inhibitori ponovne pohrane serotonina za anksioznost i opsesivno-kompulzivne simptome, psihostimulansi kod hiperaktivnosti i nepažnje). Mnogi lijekovi koji potencijalno imaju učinak na smanjenje osnovnih simptoma bolesti su trenutno u fazama istraživanja (arbaklofen i bumetanid). Nefarmakološke mjere kao što su bihevioralna terapija, terapija igrom i glazbom i nutritivne intervencije pokazale su najbolje rezultate u poboljšanju ishoda liječenja te ih treba započeti u što ranijoj dobi kako bi se maksimalizirao njihov učinak. Individualizirani pristup koji se sastoji od multidisciplinarnog tima stručnjaka i podrške obitelji obavezan je za ostvarivanje uspješno provedenih intervencija s ciljem poboljšanja kvalitete života osoba oboljelih od autizma.
Abstract (english)
Autism spectrum disorder is a pervasive developmental disorder characterized by impaired social interaction, communication and repetitive and stereotyped patterns of behavior and interests. Even though the exact cause of autism is still unknown, it is considered that autism is a complex disorder resulting from the interaction of environmental and genetic factors. ASD often manifests with a wide range of associated symptoms including anxiety, aggression, inattention, hyperactivity, sleep problems and gastrointestinal disorders. Although there are no specific medications available for the treatment of core symptoms of autism, various drugs from different pharmacotherapeutic groups have shown their usefulness in associated conditions (atypical antipsychotics for irritability and impulsivity, selective serotonin reuptake inhibitors for anxiety and obsessive-compulsive disorder, psychostimulants for hyperactivity and inattention). Many drugs that potentially reduce core symptoms are currently being tested (arbaclofen and bumetanide). Nonpharmacological interventions, including behavioural therapy, play and music therapy as well as nutritive interventions proved to be effective in improving treatment outcomes and should be started at the earliest possible age to maximise their effect. An individualized approach that consists of a multidisciplinary team of experts and family support is cruical to the successful implementation of interventions with the aim of improving the quality of life in autistic individuals.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:564441
Study programmeTitle: Pharmacy - integrated undergraduate and graduate - university study
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: sveučilišni magistar farmacije (sveučilišni magistar farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-09-26 12:18:01