prikaz prve stranice dokumenta Određivanje teških metala u dodacima prehrani za liječenje upalnih bolesti crijeva GFAAS tehnikom
Embargo period 2026-07-15
master's thesis
Određivanje teških metala u dodacima prehrani za liječenje upalnih bolesti crijeva GFAAS tehnikom
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. urn:nbn:hr:163:512227
Smrkulj, Lucija
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmaceutical analysis

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

Cite this document

Smrkulj, L. (2024). Određivanje teških metala u dodacima prehrani za liječenje upalnih bolesti crijeva GFAAS tehnikom (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:512227

Smrkulj, Lucija. "Određivanje teških metala u dodacima prehrani za liječenje upalnih bolesti crijeva GFAAS tehnikom." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. https://urn.nsk.hr/urn:nbn:hr:163:512227

Smrkulj, Lucija. "Određivanje teških metala u dodacima prehrani za liječenje upalnih bolesti crijeva GFAAS tehnikom." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. https://urn.nsk.hr/urn:nbn:hr:163:512227

Smrkulj, L. (2024). 'Određivanje teških metala u dodacima prehrani za liječenje upalnih bolesti crijeva GFAAS tehnikom', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 06 October 2024, https://urn.nsk.hr/urn:nbn:hr:163:512227

Smrkulj L. Određivanje teških metala u dodacima prehrani za liječenje upalnih bolesti crijeva GFAAS tehnikom [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2024 [cited 2024 October 06] Available at: https://urn.nsk.hr/urn:nbn:hr:163:512227

L. Smrkulj, "Određivanje teških metala u dodacima prehrani za liječenje upalnih bolesti crijeva GFAAS tehnikom", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:163:512227

Metadata
TitleOdređivanje teških metala u dodacima prehrani za liječenje upalnih bolesti crijeva GFAAS tehnikom
Title (english)Determination of heavy metals in dietary supplement therapies for inflammatory bowel disease by graphite furnace atomic absorption spectrometry
AuthorLucija Smrkulj
MentorDaniela Amidžić Klarić (mentor)
Committee memberDaniela Amidžić Klarić (predsjednik povjerenstva)
Committee memberSandra Šupraha-Goreta (član povjerenstva)
Committee memberPetra Turčić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmaceutical analysis)
Zagreb
Defense date and country2024-07-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Uključivanje dodataka prehrani standardnoj terapiji za liječenje upalnih bolesti crijeva može pozitivno djelovati na tijek i jačinu bolesti. Kurkumin, andrografolidi, piperin i bosvelične kiseline su biološki aktivne tvari biljnog podrijetla koje svojim protuupalnim, antioksidativnim, i/ili imunomodulatornim svojstvima smanjuju simptome bolesti. Cilj ovog rada bio je procijeniti kvalitetu i sigurnost dodataka prehrani s obzirom na sadržaj teških metala; arsena, kadmija i olova. Budući da su navedeni metali najčešće zastupljeni u niskim koncentracijama, odabrana je tehnika grafitne atomske apsorpcijske spektrometrije nakon postupka mikrovalne digestije. Dobiveni rezultati upućuju na niski sadržaj metala arsena i kadmija. Međutim, sadržaj olova u dva uzorka prelazi dozvoljenu dnevnu izloženost oralnom putem te njihova primjena predstavlja rizik za zdravlje ljudi. U zaključku se ističe potreba stalnog praćenja sigurnosti dodataka prehrani dostupnih na tržištu s obzirom na sadržaj olova.
Abstract (english)
The inclusion of dietary supplements in the standard therapy for the treatment of inflammatory bowel diseases can have a positive effect on the course and severity of the disease. Curcumin, andrographolides, piperine and boswellic acids are biologically active compounds from plants that reduce disease symptoms with their anti-inflammatory, antioxidant and/or immunomodulatory properties. The aim of this work was to evaluate the quality and safety of dietary supplements with regard to the content of heavy metals such as arsenic, cadmium and lead. Since the mentioned metals are primarily present in low concentrations, the graphite atomic absorption spectrometry technique was used after the microwave digestion procedure. The results indicated a low content of metals, including arsenic and cadmium. However, the lead content in two samples exceeds the permitted daily oral exposure, and their use could pose a risk to human health. In conclusion, the need for constant monitoring of the safety of dietary supplements available on the market regarding lead content is emphasized.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:512227
Study programmeTitle: Pharmacy - integrated undergraduate and graduate - university study
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: sveučilišni magistar farmacije (sveučilišni magistar farmacije)
Type of resourceText
File originBorn digital
Access conditionsEmbargoed access
Embargo expiration date: 2026-07-15
Terms of useLicence In copyright icon
Created on2024-09-27 11:35:44