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master's thesis
Lijekovi u liječenju hipersekrecije želučane kiseline
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. urn:nbn:hr:163:149868
Petras, Dora
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmacology

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

Cite this document

Petras, D. (2024). Lijekovi u liječenju hipersekrecije želučane kiseline (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:149868

Petras, Dora. "Lijekovi u liječenju hipersekrecije želučane kiseline." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. https://urn.nsk.hr/urn:nbn:hr:163:149868

Petras, Dora. "Lijekovi u liječenju hipersekrecije želučane kiseline." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2024. https://urn.nsk.hr/urn:nbn:hr:163:149868

Petras, D. (2024). 'Lijekovi u liječenju hipersekrecije želučane kiseline', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 28 March 2025, https://urn.nsk.hr/urn:nbn:hr:163:149868

Petras D. Lijekovi u liječenju hipersekrecije želučane kiseline [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2024 [cited 2025 March 28] Available at: https://urn.nsk.hr/urn:nbn:hr:163:149868

D. Petras, "Lijekovi u liječenju hipersekrecije želučane kiseline", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:163:149868

Metadata
TitleLijekovi u liječenju hipersekrecije želučane kiseline
Title (english)Medications in the treatment of gastric acid hypersecretion
AuthorDora Petras
MentorLidija Bach-Rojecky (mentor)
Committee memberLidija Bach-Rojecky (predsjednik povjerenstva)
Committee memberMaja Bival Štefan (član povjerenstva)
Committee memberLaura Nižić Nodilo (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmacology)
Zagreb
Defense date and country2024-09-09, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Želučana kiselina ključna je za normalnu probavu i apsorpciju hranjivih tvar te ima važnu ulogu u zaštiti probavnog sustava od patogena. Međutim, hipersekrecija želučane kiseline može uzrokovati značajne zdravstvene probleme, uključujući gastroezofagealnu refluksnu bolest (GERB), peptički ulkus i Zollinger-Ellisonov sindrom. Ove bolesti imaju kronični tijek, praćene su neugodnim simptomima te značajno narušavaju kvalitetu života oboljelih. Ovim preglednim radom prikazane su farmakološke... More karakteristike lijekova koji se koriste za kontrolu hipersekrecije želučane kiseline, uključujući antacide, antagoniste histaminskih H2-receptora i inhibitore protonske pumpe. Svaka od ovih skupina lijekova ima specifične mehanizme djelovanja, farmakokinetske posebnosti, prednosti i nedostake, koje je potrebno poznavati i razumjeti kako bi se za svakog pacijenta odabrao optimalni lijek. Inhibitori protonske pumpe su najučinkovitija terapija te se danas koriste kao glavna terapijska opcija kod poremećaja hiperaciditeta. Međutim, njihova dugotrajna primjena zahtijeva pažljivo praćenje zbog potencijalnih nuspojava, uključujući malapsorpciju vitamina i minerala, povećan rizik od prijeloma i infekcija. Ključnu ulogu u ispravnoj primjeni lijekova imaju ljekarnici. Kao stručnjaci za lijekove, trebaju osigurati da pacijenti razumiju zašto koriste određene lijekove i kako ih pravilno primjenjivati. Edukacija pacijenata o pravilnoj upotrebi lijekova, mogućim interakcijama i nuspojavama može značajno doprinijeti uspjehu terapije i smanjenju rizika od neželjenih posljedica. Less
Abstract (english)
Gastric acid is crucial for normal digestion and absorption of nutrients and plays an important role in protecting the digestive system from pathogens. However, hypersecretion of gastric acid can lead to significant health problems, including gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. These conditions have a chronic course, are accompanied by unpleasant symptoms, and significantly impair the quality of life of affected individuals. This... More review presents the pharmacological characteristics of drugs used to control gastric acid hypersecretion, including antacids, histamine H2-receptor antagonists, and proton pump inhibitors. Each of these drug classes has specific mechanisms of action, pharmacokinetic properties, advantages, and disadvantages that need to be understood to select the optimal medication for each patient. Proton pump inhibitors are the most effective therapy and are currently used as the main therapeutic option for hyperacidity disorders. However, their long-term use requires careful monitoring due to potential side effects, including malabsorption of vitamins and minerals, increased risk of fractures, and infections. Pharmacists play a key role in the correct application of these medications. As medication experts, they should ensure that patients understand why they are using certain drugs and how to use them properly. Educating patients on the correct use of medications, possible interactions, and side effects can significantly contribute to the success of therapy and reduce the risk of adverse outcomes. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:149868
Study programmeTitle: Pharmacy - integrated undergraduate and graduate - university study
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: sveučilišni magistar farmacije (sveučilišni magistar farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-10-10 10:55:30
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