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master's thesis
Fitokemijska karakterizacija polifenola vrste Centaurea ragusina L., Asteraceae
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2015. urn:nbn:hr:163:718043
Domitrović, Iva
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of pharmaceutical analysis

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Domitrović, I. (2015). Fitokemijska karakterizacija polifenola vrste Centaurea ragusina L., Asteraceae (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:718043

Domitrović, Iva. "Fitokemijska karakterizacija polifenola vrste Centaurea ragusina L., Asteraceae." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2015. https://urn.nsk.hr/urn:nbn:hr:163:718043

Domitrović, Iva. "Fitokemijska karakterizacija polifenola vrste Centaurea ragusina L., Asteraceae." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2015. https://urn.nsk.hr/urn:nbn:hr:163:718043

Domitrović, I. (2015). 'Fitokemijska karakterizacija polifenola vrste Centaurea ragusina L., Asteraceae', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 12 July 2024, https://urn.nsk.hr/urn:nbn:hr:163:718043

Domitrović I. Fitokemijska karakterizacija polifenola vrste Centaurea ragusina L., Asteraceae [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2015 [cited 2024 July 12] Available at: https://urn.nsk.hr/urn:nbn:hr:163:718043

I. Domitrović, "Fitokemijska karakterizacija polifenola vrste Centaurea ragusina L., Asteraceae", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2015. Available at: https://urn.nsk.hr/urn:nbn:hr:163:718043

Metadata
TitleFitokemijska karakterizacija polifenola vrste Centaurea ragusina L., Asteraceae
Title (english)Phytochemical characterization of polyphenols from Centaurea ragusina L., Asteraceae
AuthorIva Domitrović
MentorRenata Jurišić Grubešić (mentor)
Committee memberRenata Jurišić Grubešić
Committee memberDario Kremer
Committee memberŽivka Juričić
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmaceutical analysis)
Zagreb
Defense date and country2015-06-29, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
U okviru ovoga diplomskog rada provedena je fitokemijska karakterizacija endemske vrste Centaurea ragusina L., Asteraceae. Prisutnost polifenolnih tvari dokazana je općim reakcijama stvaranja obojenih produkata ili taloga. Provedbom tankoslojne kromatografije potvrđena je prisutnost kvercetina, rutina i klorogenske kiseline u metanolnom ekstraktu dubrovačke zečine. Kvantitativna analiza ukupnih polifenola (UP), trjeslovina (T), flavonoida (F) i fenolnih kiselina (FK) provedena je spektrofotometrijskim metodama. Sadržaj analiziranih polifenolnih tvari iznosio je: 3,04±0,04% (UP), 0,36±0,04% (T), 0,25±0,00% (F) i 0,38±0,01% (FK). Provedena fitokemijska karakterizacija predstavlja prilog znanstvenom istraživanju hrvatskih endema i upotpunjuje dosadašnje spoznaje o fitoterapijskom potencijalu dubrovačke zečine, posebice u odnosu na sadržaj bioaktivnih polifenolnih tvari.
Abstract (english)
In this work, phytochemical characterization of an endemic species, Centaurea ragusina L. (Asteraceae) was carried out. The presence of polyphenols was proven by using general reactions of developing colored products and precipitates. The thin layer chromatography revealed the presence of quercetin, rutin, and chlorogenic acid in the methanolic extract. Quantitative analysis of total polyphenols (TP), tannins (T), flavonoids (F), and phenolic acids (PA) was carried out using the spectrophotometric methods. The contents of analyzed polyphenolic compounds were as follows: 3.04±0.04% (TP), 0.36±0.04% (T), 0.25±0.00% (F), and 0.38±0.01% (PA). Performed phytochemical characterization is a contribution to the scientific study of Croatian endemic species and completes the existing knowledge about phytotherapeutic potential of C. ragusina, especially in relation to the content of bioactive polyphenolic substances.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:718043
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2016-01-18 13:40:16