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master's thesis
Sinteza i karakterizacija tiolno funkcionaliziranih nanočestica srebra i zlata
Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry, 2016. urn:nbn:hr:163:829648
Ivanković, Fran
University of Zagreb
Faculty of Pharmacy and Biochemistry
Department of organic chemistry

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Ivanković, F. (2016). Sinteza i karakterizacija tiolno funkcionaliziranih nanočestica srebra i zlata (Master's thesis). Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:829648

Ivanković, Fran. "Sinteza i karakterizacija tiolno funkcionaliziranih nanočestica srebra i zlata." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2016. https://urn.nsk.hr/urn:nbn:hr:163:829648

Ivanković, Fran. "Sinteza i karakterizacija tiolno funkcionaliziranih nanočestica srebra i zlata." Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, 2016. https://urn.nsk.hr/urn:nbn:hr:163:829648

Ivanković, F. (2016). 'Sinteza i karakterizacija tiolno funkcionaliziranih nanočestica srebra i zlata', Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, accessed 26 November 2024, https://urn.nsk.hr/urn:nbn:hr:163:829648

Ivanković F. Sinteza i karakterizacija tiolno funkcionaliziranih nanočestica srebra i zlata [Master's thesis]. Zagreb: University of Zagreb, Faculty of Pharmacy and Biochemistry; 2016 [cited 2024 November 26] Available at: https://urn.nsk.hr/urn:nbn:hr:163:829648

F. Ivanković, "Sinteza i karakterizacija tiolno funkcionaliziranih nanočestica srebra i zlata", Master's thesis, University of Zagreb, Faculty of Pharmacy and Biochemistry, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:163:829648

Metadata
TitleSinteza i karakterizacija tiolno funkcionaliziranih nanočestica srebra i zlata
Title (english)Synthesis and characterization of thiole functionalized silver and gold nanoparticles
AuthorFran Ivanković
MentorValerije Vrček (mentor)
MentorIvana Vinković Vrček (mentor)
MBZ: 264334
Committee memberValerije Vrček (predsjednik povjerenstva)
Committee memberDavor Šakić (član povjerenstva)
Committee memberIvana Vinković Vrček (član povjerenstva)
MBZ: 264334
GranterUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of organic chemistry)
Zagreb
Defense date and country2016-10-11, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract
Za sintezu nanočestica srebra i zlata definiranih fizikalno-kemijskih svojstava ključno je odabrati prikladnu strategiju sinteze. Veličina, oblik i stabilnost nanočestica mogu se podešavati regulacijom molarnih omjera reaktanata te redoslijedom dodavanja reaktanata. U ovom radu su dvjema metodama sintetizirane nanoAg funkcionalizirane cisteinom ili glutationom te nanoAu funkcionalizirane cisteinom i glutationom. Karakterizacija i procjena stabilnosti provedena je primjenom različitih eksperimentalnih tehnika: atomske apsorpcijske spektroskopije (AAS), dinamičke metode raspršenja svjetlosti, elektroforetske metode raspršenja svjetlosti, transmisijske elektronske mikroskopije, te metode nuklearne magnetne rezonance. Otkriveno je da funkcionalizacija glutationom i cisteinom rezultira vrlo stabilnim nanočesticama srebra i zlata, uglavnom sfernoga oblika, čiji promjer i distribucija veličina izravno ovisi o molarnim omjerima reaktanata. Metodom nuklearne magnetske rezonancije zaključeno je da stabilizator ostvaruje strukturni kontakt sa nanočesticom preko tiolne i karboksilne skupine.
Abstract (english)
In order to synthesize silver and gold nanoparticles with defined physical-chemical properties it is essential to choose an adequate sythesis strategy. Size, shape and stability of nanoparticles can be adjusted by regulating the molar ratios of reactants and the order of adding the reactants. In this thesis two methods were used to sythesize nanoAg functionalized by cysteine or glutathione and nanoAu functionalized by cysteine or glutathione. Characterization and evaluation of stability was conducted by using various experimental techniques: atomic apsorption spectroscopy (AAS), dynamic light scattering, electroforetic light scattering, transmission electron microscopy and nuclear magnetic resonance. It was discovered that functionalization by glutathione and cysteine results in very stable silver and gold nanoparticles, mostly spheric in shape, whose diameter and size distribution directly depends on the molar ratio of reactants. By using the nuclear magnetic resonance method it was discovered that the stabiliser forms structural contact with the nanoparticle through the thiole and carboxyle group.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:163:829648
Study programmeTitle: Pharmacy
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra farmacije (magistar/magistra farmacije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2016-12-05 11:28:59