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Scientific paper - Original scientific paper
Razvoj i validacija HSS-GC-FID metode za određivanje sadržaja lakohlapljivih sastavnica sirupa za iskašljavanje za djecu
Farmaceutski glasnik, 69 (2013), 3; 155-166. urn:nbn:hr:163:852854
Mornar, Ana; Sertić, Miranda; NIgović, Biljana; Lepan, Biljana; Zovko Končić, Marijana

Institutional repository: Repository of Faculty of Pharmacy and Biochemistry University of Zagreb

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Mornar, A., Sertić, M., NIgović, B., Lepan, B. & Zovko Končić, M. (2013). Razvoj i validacija HSS-GC-FID metode za određivanje sadržaja lakohlapljivih sastavnica sirupa za iskašljavanje za djecu. Farmaceutski glasnik, 69. (3), 155-166. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:852854

Mornar, Ana, et al. "Razvoj i validacija HSS-GC-FID metode za određivanje sadržaja lakohlapljivih sastavnica sirupa za iskašljavanje za djecu." Farmaceutski glasnik, vol. 69, no. 3, 2013, pp. 155-166. https://urn.nsk.hr/urn:nbn:hr:163:852854

Mornar, Ana, Miranda Sertić, Biljana NIgović, Biljana Lepan and Marijana Zovko Končić. "Razvoj i validacija HSS-GC-FID metode za određivanje sadržaja lakohlapljivih sastavnica sirupa za iskašljavanje za djecu." Farmaceutski glasnik 69, no. 3 (2013): 155-166. https://urn.nsk.hr/urn:nbn:hr:163:852854

Mornar, A., et al. (2013) 'Razvoj i validacija HSS-GC-FID metode za određivanje sadržaja lakohlapljivih sastavnica sirupa za iskašljavanje za djecu', Farmaceutski glasnik, 69(3), pp. 155-166. Available at: https://urn.nsk.hr/urn:nbn:hr:163:852854 (Accessed 22 November 2024)

Mornar A, Sertić M, NIgović B, Lepan B, Zovko Končić M. Razvoj i validacija HSS-GC-FID metode za određivanje sadržaja lakohlapljivih sastavnica sirupa za iskašljavanje za djecu. Farmaceutski glasnik [Internet]. 2013 [cited 2024 November 22];69(3):155-166. Available at: https://urn.nsk.hr/urn:nbn:hr:163:852854

A. Mornar, M. Sertić, B. NIgović, B. Lepan and M. Zovko Končić, "Razvoj i validacija HSS-GC-FID metode za određivanje sadržaja lakohlapljivih sastavnica sirupa za iskašljavanje za djecu", Farmaceutski glasnik, vol. 69, no. 3, pp. 155-166, 2013. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:852854. [Accessed: 22 November 2024]

Metadata
Title (croatian)Razvoj i validacija HSS-GC-FID metode za određivanje sadržaja lakohlapljivih sastavnica sirupa za iskašljavanje za djecu
AuthorAna Mornar
AuthorMiranda Sertić
AuthorBiljana NIgović
AuthorBiljana Lepan
AuthorMarijana Zovko Končić
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmaceutical analysis)
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of pharmacognosy)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract (english)
A cough syrup is a medicinal product used in an attempt to treat coughing and related conditions. Traditional herbs are used for preparation of cough syrup. There are two main categories of herbs that are used in preparation of cough remedies: expectorants and antitussives. For productive coughs, treatment with expectorants may be attempted to loosen mucus from the respiratory tract. For dry coughs antitussives are used to suppress the body’s urge to cough. Herbal medicinal products may contain significant levels of ethanol arising from its use as an extraction solvent in liquid extracts and tinctures. Although the use of ethanol is necessary for extraction of pharmacologically active compounds, it was found that some herbal medicinal products contain large amounts (up to 60 %) of ethanol with even less clinical need or benefit. In young children ingestion of even modest amounts of ethanol may lead to permanent neurological damage as result of hypoglycemia. Therefore, special attention should be given to the ethanol content of herbal medicinal products for pediatric use. At the moment the safety evaluation of the ethanol content of herbal medicinal products for pediatric use is not harmonized between different European Union Member States. Moreover, the lack of guidelines relating to safe limits of ethanol as part of herbal medicinal products for pediatric use has also led to different national labeling practices. Therefore, the aim of our work was to develop and validate a new HSS-GC-FID method for quantification of ethanol and its main impurity, methanol, present in children’s cough syrup.
Keywords (croatian)
Languagecroatian
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - domestic
Publication versionPublished version
Journal titleFarmaceutski glasnik
Numberingvol. 69, no. 3, pp. 155-166
p-ISSN0014-8202
URN:NBNurn:nbn:hr:163:852854
Publication2013
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-11-28 15:30:47