prikaz prve stranice dokumenta Antimicrobial activity of some hydroxamic acids
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Scientific paper - Original scientific paper
Antimicrobial activity of some hydroxamic acids
Acta Pharmaceutica, 55 (2005), 4; 401-408. urn:nbn:hr:163:343095
Pepeljnjak, Stjepan; Zorc, Branka; Butula, Ivan

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Pepeljnjak, S., Zorc, B. & Butula, I. (2005). Antimicrobial activity of some hydroxamic acids. Acta Pharmaceutica, 55. (4), 401-408. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:343095

Pepeljnjak, Stjepan, et al. "Antimicrobial activity of some hydroxamic acids." Acta Pharmaceutica, vol. 55, no. 4, 2005, pp. 401-408. https://urn.nsk.hr/urn:nbn:hr:163:343095

Pepeljnjak, Stjepan, Branka Zorc and Ivan Butula. "Antimicrobial activity of some hydroxamic acids." Acta Pharmaceutica 55, no. 4 (2005): 401-408. https://urn.nsk.hr/urn:nbn:hr:163:343095

Pepeljnjak, S., Zorc, B. and Butula, I. (2005) 'Antimicrobial activity of some hydroxamic acids', Acta Pharmaceutica, 55(4), pp. 401-408. Available at: https://urn.nsk.hr/urn:nbn:hr:163:343095 (Accessed 22 November 2024)

Pepeljnjak S, Zorc B, Butula I. Antimicrobial activity of some hydroxamic acids. Acta Pharmaceutica [Internet]. 2005 December 01 [cited 2024 November 22];55(4):401-408. Available at: https://urn.nsk.hr/urn:nbn:hr:163:343095

S. Pepeljnjak, B. Zorc and I. Butula, "Antimicrobial activity of some hydroxamic acids", Acta Pharmaceutica, vol. 55, no. 4, pp. 401-408, December 2005. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:343095. [Accessed: 22 November 2024]

Metadata
Title (english)Antimicrobial activity of some hydroxamic acids
Title (croatian)Antimikrobni učinak nekih hidroksamskih kiselina
AuthorStjepan Pepeljnjak
AuthorBranka Zorc
AuthorIvan Butula
MBZ: 6372
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of medicinal chemistry)
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of microbiology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract (english)
Several hydroxamic acids, viz., N-benzyl-N'-hydroxysuccinamide (BHS) (1), poly[alpha,beta-(N-hydroxy)-DL-aspartamide] (PHA) (2), poly[alpha,beta-(N-hydroxy-N-methyl-DL-aspartamide)] (PMHA) (3) and poly [alpha,beta-(N-hydroxy)-DL-aspartamide]/poly[alpha,beta-(N-2-hydroxyethyl)-DL-aspartamide] (PHA-PHEA 1:1) (4) were prepared and screened for their antimicrobial activity. Ten Gram-positive and 7 Gram-negative species of bacteria, 5 Candida species, 4 dermatophytes species and 3 mould species were used in tests. Compound 1 showed no antimicrobial activity on any of the tested microorganisms. Other compounds (2-4) showed a narrow spectrum of antibacterial activity, but no antifungal activity.
Abstract (croatian)
U radu je ispitano antimikrobno djelovanje nekoliko hidroksamskih kiselina: N-benzil-N’-hidroksi-sukcinamida (BHS) (1), poli[alpha,beta-(N-hidroksi)-DL-aspartamida](PHA) (2), poli[alpha,beta-(N-hidroksi-N-metil-DL-aspartamida)](PMHA) (3) i poli[alpha,beta-(N-hidroksi)-DL-aspartamid]/poli[alpha,beta-(N-2- -hidroksietil)-DL-aspartamid] kopolimera (PHA-PHEA) (4). Antimikrobno djelovanje ispitano je na 10 Gram-pozitivnih i 7 Gram-negativnih bakterija, 5 vrsta kandida, 4 vrste dermatofita i 3 vrste plijesni. Supstancija 1 ne pokazuje antimikrobno djelovanje na ispitivane vrsta bakterija i gljivica. Ostali spojevi (2–4) imaju relativno slabo antimikrobno djelovanje na Gram-pozitivne i Gram-negativne bakterije i ne pokazuju antifungalni učinak.
Keywords (english)
Keywords (croatian)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleActa Pharmaceutica
Numberingvol. 55, no. 4, pp. 401-408
p-ISSN1330-0075
e-ISSN1846-9558
URN:NBNurn:nbn:hr:163:343095
Publication2005-12-01
Document URLhttps://hrcak.srce.hr/19045
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-02-14 13:43:47