prikaz prve stranice dokumenta Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres.
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Scientific paper - Original scientific paper
Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres.
Acta Pharmaceutica, 55 (2005), 4; 357-364. urn:nbn:hr:163:549496
Kosalec, Ivan; Šegvić Klarić, Maja; Pepeljnjak, Stjepan

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Kosalec, I., Šegvić Klarić, M. & Pepeljnjak, S. (2005). Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres.. Acta Pharmaceutica, 55. (4), 357-364. Retrieved from https://urn.nsk.hr/urn:nbn:hr:163:549496

Kosalec, Ivan, et al. "Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres.." Acta Pharmaceutica, vol. 55, no. 4, 2005, pp. 357-364. https://urn.nsk.hr/urn:nbn:hr:163:549496

Kosalec, Ivan, Maja Šegvić Klarić and Stjepan Pepeljnjak. "Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres.." Acta Pharmaceutica 55, no. 4 (2005): 357-364. https://urn.nsk.hr/urn:nbn:hr:163:549496

Kosalec, I., Šegvić Klarić, M. and Pepeljnjak, S. (2005) 'Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres.', Acta Pharmaceutica, 55(4), pp. 357-364. Available at: https://urn.nsk.hr/urn:nbn:hr:163:549496 (Accessed 25 November 2024)

Kosalec I, Šegvić Klarić M, Pepeljnjak S. Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres.. Acta Pharmaceutica [Internet]. 2005 December 01 [cited 2024 November 25];55(4):357-364. Available at: https://urn.nsk.hr/urn:nbn:hr:163:549496

I. Kosalec, M. Šegvić Klarić and S. Pepeljnjak, "Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres.", Acta Pharmaceutica, vol. 55, no. 4, pp. 357-364, December 2005. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:163:549496. [Accessed: 25 November 2024]

Metadata
Title (english)Verruculogen production in airborne and clinical isolates of Aspergillus fumigatus Fres.
Title (croatian)Tvorba verukulogena u kliničkih i iz zraka izoliranih sojeva vrste Aspergillus fumigatus Fres.
AuthorIvan Kosalec
AuthorMaja Šegvić Klarić
AuthorStjepan Pepeljnjak
Author's institutionUniversity of Zagreb
Faculty of Pharmacy and Biochemistry
(Department of microbiology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Pharmacy
Pharmacy
Abstract (english)
Among airborne aspergilli sampled in outdoor air of the Zagreb area (2002/2003), Aspergillus niger (v. Teigh.) and A. fumigatus (Fres.) were the most abundant species (20-30%), with low mean annual concentrations (0.21-1.04 CFU m-3). Higher concentrations of A. fumigatus were observed in autumn and winter (0.5-1.05 CFU m-3) than in spring and summer (0-0.4 CFU m-3). On the other hand, A. fumigatus was found to be the most frequent isolate from upper and/or lower respiratory tracts of imunocompromised patients in many studies. This species produces several mycotoxins including the tremorgenic mycotoxin verruculogen that can be found in spores and during myceliar growth. Verruculogen production ability was tested by biosynthesis on 30 airborne and 33 clinical isolates of A. fumigatus. In both groups, high percentage of verruculogen-producing strains was noticed (84% of airborne and 91% of clinical isolates). Verruculogen production was not significantly different in the groups of airborne isolates (0.34 ± 0.16 mg mL-1) and clinical isolates (0.26 ± 0.19 mg mL-1, p > 0.05).
Abstract (croatian)
Uzorkovanje spora plijesni na području grada Zagreba obavljeno je tijekom godine 2002./2003. Pri tome su Aspergillus niger (v. Teigh.) i A. fumigatus (Fres.) bile najučestalije (20–30%) među aerogenim Aspergillus vrstama. Srednje godišnje koncentracije njihovih spora bile su izrazito niske (0,21–1,04 CFU m–3). Veće koncentracije spora A. fumigatus zabilježene su tijekom jeseni i zime (0,50–1,05 CFU m–3) u odnosu na koncentracije izmjerene tijekom proljeća i ljeta (0–0,40 CFU m–3). S druge strane, mnogobrojne studije ukazuju na visoku učestalost A. fumigatus izolata iz gornjih i donjih dišnih puteva imunokompromitiranih bolesnika. Ova plijesan tvori nekoliko različitih mikotoksina, uključujući i tremorgeni mikotoksin verukulogen koji se može naći u sporama i miceliju vrste A. fumigatus. Tvorba verukulogena ispitana je u 30 aerogenih i 33 klinička izolata A. fumigatus vrste. U obje skupine dokazana je visoka učestalost verukulogen-pozitivnih sojeva (84% aerogenih i 91% kliničkih izolata). Potencijal tvorbe verukulogena u aerogenih (0.34 ± 0.16 mg mL–1) i kliničkih sojeva (0.26 ± 0.19 mg mL–1) nije se značajnije razlikovao.
Keywords (english)
Keywords (croatian)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleActa Pharmaceutica
Numberingvol. 55, no. 4, pp. 357-364
p-ISSN1330-0075
e-ISSN1846-9558
URN:NBNurn:nbn:hr:163:549496
Publication2005-12-01
Document URLhttps://hrcak.srce.hr/18119
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-02-27 12:21:57