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master's thesis
Doze izvan ciljnog volumena pri neuroradiokirurgiji uređajem gama nož
Zagreb: University of Zagreb, Faculty of Science, 2021. urn:nbn:hr:217:040863
Polović, Alen
University of Zagreb
Faculty of Science
Department of Mathematics

Institutional repository: Repository of the Faculty of Science

Cite this document

Polović, A. (2021). Doze izvan ciljnog volumena pri neuroradiokirurgiji uređajem gama nož (Master's thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:040863

Polović, Alen. "Doze izvan ciljnog volumena pri neuroradiokirurgiji uređajem gama nož." Master's thesis, University of Zagreb, Faculty of Science, 2021. https://urn.nsk.hr/urn:nbn:hr:217:040863

Polović, Alen. "Doze izvan ciljnog volumena pri neuroradiokirurgiji uređajem gama nož." Master's thesis, University of Zagreb, Faculty of Science, 2021. https://urn.nsk.hr/urn:nbn:hr:217:040863

Polović, A. (2021). 'Doze izvan ciljnog volumena pri neuroradiokirurgiji uređajem gama nož', Master's thesis, University of Zagreb, Faculty of Science, accessed 23 December 2024, https://urn.nsk.hr/urn:nbn:hr:217:040863

Polović A. Doze izvan ciljnog volumena pri neuroradiokirurgiji uređajem gama nož [Master's thesis]. Zagreb: University of Zagreb, Faculty of Science; 2021 [cited 2024 December 23] Available at: https://urn.nsk.hr/urn:nbn:hr:217:040863

A. Polović, "Doze izvan ciljnog volumena pri neuroradiokirurgiji uređajem gama nož", Master's thesis, University of Zagreb, Faculty of Science, Zagreb, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:217:040863

Metadata
TitleDoze izvan ciljnog volumena pri neuroradiokirurgiji uređajem gama nož
Title (english)Doses outside the target volume in neuroradesurgery with a gamma knife device
AuthorAlen Polović
MentorMarija Majer (mentor)
Committee memberMarija Majer (predsjednik povjerenstva)
Committee memberIlja Gogić (član povjerenstva)
Committee memberTomislav Bokulić (član povjerenstva)
Committee memberMatija Kazalicki (član povjerenstva)
Committee memberMihael Makek (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Science
(Department of Mathematics)
Zagreb
Defense date and country2021-09-22, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Mathematics
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Physics
Abstract
U ovom radu izmjerene su doze izvan ciljnog volumena prilikom radioneurokirurškog zahvata uređajem Leksell Gamma Knife Icon. Korišteni su termoluminiscentni dozimetri na bazi LiF sa primjesama Mg i Ti, poznatiji kao TLD-700. Doze su mjerene u antropomorfnom fantomu koji predstavlja desetogodišnje dijete oba spola. Iako se ionizirajuće zračenje prilikom radioneurokirurškog tretmana prvobitno koristi za dobrobit pacijenta, ono može izazvati neželjene učinke u organizmu. Posebna pozornost je usmjerena prema dozama izvan ciljnog volumena koje apsorbiraju djeca, budući da je organizam u razvoju posebno osjetljiv na ionizirajuće zračenje. Na osnovi rezultata mjerenja apsorbiranih doza određena je srednja doza koju apsorbira štitnjača prilikom medicinskog oslikavanja pridruženim uređajem za računalnu tomografiju stožastim snopom, raspodjela doza apsorbiranih prilikom tretmana uređajem Leksell Gamma Knife Icon u ovisnosti o udaljenosti od ciljnog volumena, raspodjela doza apsorbiranih prilikom tretmana uređajem Leksell Gamma Knife Icon u organima i usporedba dobivene raspodjele doze u organima sa dozama izmjerenim prilikom ozračivanja istog ciljnog volumena koristeći uređaj Leksell Gamma Knife Model C, te radioterapijske tehnike koje koriste fotonske (IMRT) i protonske (IMPT) snopove. Doze apsorbirane prilikom tretmana uređajem Leksell Gamma Knife Icon višestruko su manje nego doze apsorbirane prilikom tretmana uređajem Leksell Gamma Knife Model C, približno su jednake dozama apsorbiranim prilikom tretmana fotonskim snopom i višestruko veće od doza apsorbiranih prilikom tretmana protonskim snopom.
Abstract (english)
In this work, doses outside the target volume were measured during radioneurosurgery using Leksell Gamma Knife Icon. LiF-based thermoluminescent dosimeters with Mg and Ti admixtures, better known as TLD-700, were used. Doses were measured in an anthropomorphic phantom representing a ten-year-old child of both sexes. Although ionizing radiation during radioneurosurgical treatment is originally used for benefiting the patient, it can cause side e ects in the body. Particular attention is paid to doses outside the target volume absorbed by children, as the developing organism is particularly sensitive to ionizing radiation. Based on measurements of absorbed doses, the mean dose absorbed by the thyroid gland during medical imaging with the Cone Beam Computed Tomography device was determined, along with the distance dependence of absorbed doses during treatment using Leksell Gamma Knife Icon, organ distribution of doses during treatment using Leksell Gamma Knife Icon and comparison of the obtained dose distribution in the organs with the doses measured when irradiating the same target volume using the Leksell Gamma Knife Model C, and radiotherapy techniques using photon (IMRT) and proton (IMPT) bundles. Doses absorbed during treatment with Leksell Gamma Knife Icon are many times smaller than doses absorbed during treatment with Leksell Gamma Knife Model C, approximately equal to doses absorbed during photon beam treatment and many times higher than doses absorbed during proton beam treatment.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:040863
Study programmeTitle: Mathematics and Physics Education; specializations in: Mathematics and Physics Education
Course: Mathematics and Physics Education
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: magistar/magistra edukacije matematike i fizike (magistar/magistra edukacije matematike i fizike)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-11-05 11:20:08