In this thesis, three ferrocene amide derivatives of mannosylated desmuramyl dipeptide with varying length of the alkyl chain connecting the ferrocene subunit with the rest of the molecule have been synthesized. Ferrocene amines with three and four methylene groups were prepared from the corresponding protected amines by removal of the Boc protective group. Ferrocene amine with two methylene groups has been prepared by reduction of ferroceneacetonitrile. BocL-Ala-D-isoGln was used as the peptide subunit and prepared by removing the benzyl protective group from the corresponding commercially available Boc-L-Ala-D-isoGln(OBn). 2,3,4,6- tetra-O-acetyl-α-D-mannopyranose was used for the preparation of the mannose subunit by its reaction with tert-butyl bromoacetate and subsequent removal of the tert-butyl protective group in acidic condition. Ferrocene amines were connected through an amide bond to desmuramyl dipeptide via the carboxyl group located on the isoGln side chain. For this purpose reaction with EDC×HCl as a condensation reagent, HOBt as an additive and TEA as a base was used. After the removal of the peptide Boc protective group, ferrocene amide derivatives of desmuramyl dipeptide were linked to the mannose subunit in the same amidation reaction conditions. The final step in the synthesis of the target products was the removal of the acetyl protective groups from the mannose subunit, which was achieved by Zemplén's procedure. Thus, the final products were succesfully obtained and will be used for the investigation of their adjuvant activity.