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undergraduate thesis
Nepravilnosti u mitozi i mejozi – bolesti i evolucija
Zagreb: University of Zagreb, Faculty of Science, 2022. urn:nbn:hr:217:557809
Šimić, Lucija
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Šimić, L. (2022). Nepravilnosti u mitozi i mejozi – bolesti i evolucija (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:557809

Šimić, Lucija. "Nepravilnosti u mitozi i mejozi – bolesti i evolucija." Undergraduate thesis, University of Zagreb, Faculty of Science, 2022. https://urn.nsk.hr/urn:nbn:hr:217:557809

Šimić, Lucija. "Nepravilnosti u mitozi i mejozi – bolesti i evolucija." Undergraduate thesis, University of Zagreb, Faculty of Science, 2022. https://urn.nsk.hr/urn:nbn:hr:217:557809

Šimić, L. (2022). 'Nepravilnosti u mitozi i mejozi – bolesti i evolucija', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 04 November 2024, https://urn.nsk.hr/urn:nbn:hr:217:557809

Šimić L. Nepravilnosti u mitozi i mejozi – bolesti i evolucija [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2022 [cited 2024 November 04] Available at: https://urn.nsk.hr/urn:nbn:hr:217:557809

L. Šimić, "Nepravilnosti u mitozi i mejozi – bolesti i evolucija", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:217:557809

Metadata
TitleNepravilnosti u mitozi i mejozi – bolesti i evolucija
Title (english)berrations in Mitosis and Meiosis – Disorders and the Evolution
AuthorLucija Šimić
MentorVišnja Besendorfer (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2022-09-21, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Tijekom razvoja eukariota pojavili su se procesi mitoze i mejoze, a o njihovoj važnosti govori i činjenica da su rašireni među svim živućim eukariotima. Za razvoj mitoze bila je ključna pojava mitohondrija, a homolozi svih važnijih mitotskih molekula pronađeni su prokariotima. Evolucija mejoze je kontroverznija te se može podijeliti u dvije teorije: mejoza se razvila iz bakterijske transformacije i mejoza se razvila iz mitoze. Kod svih eukariotskih organizama su pronađeni mejotski geni, što pokazuje da, prema današnjim dokazima, nije postojao period u eukariotskoj evoluciji gdje mejoza nije bila prisutna. Bolesti u mitozi i mejozi su uzrokovane nepravilnim razdvajanjem sestrinskih kromatida ili homolognih kromosoma, što rezultira aneuploidnim brojem kromosoma. Mitotske aneuploidije kod ljudi mogu dovesti do nastanka raka, dok mejotske aneuploidije najčešće rezultiraju trisomijama i monosomijama. Aneuploidije spolnih kromosoma se bolje podnose u odnosu na autosomalne zbog inaktivacije svih kopija kromosoma X osim jedne ili malog broja gena prisutnih na kromosomu Y.
Abstract (english)
The processes of mitosis and meiosis appeared during the development of eukaryotes, and the fact that they are spread among all living eukaryotes speaks of their importance. The appearance of mitochondria was crucial for the development of mitosis, and homologues of all important mitotic molecules have been found in prokaryotes. The evolution of meiosis is more controversial and can be divided into two theories: meiosis evolved from bacterial transformation and meiosis evolved from mitosis. Meiotic genes have been found in all eukaryotic organisms, which shows that, according to today's evidence, there was no period in eukaryotic evolution where meiosis was not present. Disorders in mitosis and meiosis are caused by nondisjunction of sister chromatids or homologous chromosomes, resulting in an aneuploid number of chromosomes. Mitotic aneuploidies in humans can lead to cancer, while meiotic aneuploidies most often result in trisomies and monosomies. Sex chromosome aneuploidies are more tolerable than autosomal ones due to the inactivation of all copies of the X chromosome except for one or a small number of genes present on the Y chromosome.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:557809
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-10-06 12:37:56