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undergraduate thesis
Klinička primjena CAR-T imunoterapije
Zagreb: University of Zagreb, Faculty of Science, 2022. urn:nbn:hr:217:495604
Klasić, Franko
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Klasić, F. (2022). Klinička primjena CAR-T imunoterapije (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:495604

Klasić, Franko. "Klinička primjena CAR-T imunoterapije." Undergraduate thesis, University of Zagreb, Faculty of Science, 2022. https://urn.nsk.hr/urn:nbn:hr:217:495604

Klasić, Franko. "Klinička primjena CAR-T imunoterapije." Undergraduate thesis, University of Zagreb, Faculty of Science, 2022. https://urn.nsk.hr/urn:nbn:hr:217:495604

Klasić, F. (2022). 'Klinička primjena CAR-T imunoterapije', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 13 May 2024, https://urn.nsk.hr/urn:nbn:hr:217:495604

Klasić F. Klinička primjena CAR-T imunoterapije [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2022 [cited 2024 May 13] Available at: https://urn.nsk.hr/urn:nbn:hr:217:495604

F. Klasić, "Klinička primjena CAR-T imunoterapije", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:217:495604

Metadata
TitleKlinička primjena CAR-T imunoterapije
Title (english)Clinical application of CAR-T immunotherapy
AuthorFranko Klasić
MentorNada Oršolić (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2022-09-20, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Pojava malignih oboljenja danas je sve češća. Potreba za novim oblicima terapija nužna je za liječenje sve većeg broja onkoloških pacijenata. CAR-T imunoterapija danas predstavlja obećavajući pristup liječenju brojnih bolesti, uključujući razne malignitete poput hematoloških i solidnih tumora, ali svoju primjenu mogla bi naći i u liječenju autoimunih bolesti u budućnosti. Specifično prepoznavanje antigena kao najznačajnija karakteristika CAR-T stanica omogućuje precizno usmjeravanje CAR-T imunoterapije na bolesne stanice i tkiva. Visoka cijena i zahtjevnost proizvodnje CAR-T stanica ograničava njen pristup velikom broju pacijenata. Istraživanja koja su usmjerena na otkrivanje novih načina kreiranja CAR-T stanica te istraživanja usmjerena na otkrivanje specifičnih antigena na koje se mogu usmjeriti CAR-T stanice doprinijet će u otkrivanju punog potencijala ovog oblika imunoterpaije.
Abstract (english)
The occurrence of malignancies is on the rise. The need for development of new types of immunotherapy is crucial for treating a rising number of oncological patients. CAR-T immunotherapy gives a promising approach in threating number of diseases, including a number of haematological malignancies and solid tumors, but also CAR-T immunotherapy in future could be used for treating autoimmune disease. Specific recognition of antigens as the main characteristic of CAR-T cells provides a precise targeting of abnormal cells and tissues. High price and challenges in creating CAR-T cells make them less available to the number of patients. Researches that are amid towards finding new ways of creating CAR-T cells and researches aimed towards finding specific antigens that CAR-T cells can target will make a contribution to discovering the full potential that can be used from this type of immunotherapy.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:495604
Study programmeTitle: Ecology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-10-12 09:19:38