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undergraduate thesis
Upala i rast tumora: signalni putevi kao cilj u terapiji tumora
Zagreb: University of Zagreb, Faculty of Science, 2023. urn:nbn:hr:217:516947
Jukić, Filip
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Jukić, F. (2023). Upala i rast tumora: signalni putevi kao cilj u terapiji tumora (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:516947

Jukić, Filip. "Upala i rast tumora: signalni putevi kao cilj u terapiji tumora." Undergraduate thesis, University of Zagreb, Faculty of Science, 2023. https://urn.nsk.hr/urn:nbn:hr:217:516947

Jukić, Filip. "Upala i rast tumora: signalni putevi kao cilj u terapiji tumora." Undergraduate thesis, University of Zagreb, Faculty of Science, 2023. https://urn.nsk.hr/urn:nbn:hr:217:516947

Jukić, F. (2023). 'Upala i rast tumora: signalni putevi kao cilj u terapiji tumora', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 25 November 2024, https://urn.nsk.hr/urn:nbn:hr:217:516947

Jukić F. Upala i rast tumora: signalni putevi kao cilj u terapiji tumora [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2023 [cited 2024 November 25] Available at: https://urn.nsk.hr/urn:nbn:hr:217:516947

F. Jukić, "Upala i rast tumora: signalni putevi kao cilj u terapiji tumora", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:217:516947

Metadata
TitleUpala i rast tumora: signalni putevi kao cilj u terapiji tumora
Title (english)Inflammation and tumor growth: signaling pathways as a goal in tumor therapy
AuthorFilip Jukić
MentorNada Oršolić (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2023-09-19, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Upala je imunosni odgovor organizma na neki patogen ili vlastite oštećene stanice. Akutna upala prestaje nakon što se ukloni iritans i dolazi do ponovne uspostave homeostaze. Međutim kronična upala može imati vrlo negativne posljedice po organizam, od kroničnih bolesti sve do pojave raka. Kronična upala potiče progresiju tumora i rezistenciju na lijekove. Brojni citokini, kemokini, čimbenici rasta i imunosne stanice sudjeluju kao promotori rasta tumora. Upalni signalni putevi poput JAK-STAT, NF- B, MAPK središnji su regulatori u upalnom procesu. Bliska veza kronične upale i raka, tj. imunosnog sustava predmet je ovog rada kao i pregled novih pristupa u liječenju i prevenciji raka, a upravo signalni putevi su jedni od glavnih ciljeva.
Abstract (english)
Inflammation is the body's immune response to a pathogen or its own damaged cells. Acute inflammation resolves after the irritant is removed and homeostasis is re-established. However, chronic inflammation can have very negative consequences for the body, from chronic diseases to the appearance of cancer. Chronic inflammation promotes tumor progression and treatement resistance. Numerous cytokines, chemokines, growth factors and immune cells participate as promoters of tumor growth. Inflammatory signaling pathways such as JAK-STAT, NF-B, MAPK are central regulators in the inflammatory process. The close connection between chronic inflammation and cancer, i.e. the immune system, is the subject of this paper as well a review of new approaches to the treatment and prevention of cancer, and signaling pathways are one of the main targets.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:516947
Study programmeTitle: Ecology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-09-20 12:44:12