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undergraduate thesis
Uloga retinoične kiseline u diferencijaciji matičnih stanica sisavaca
Zagreb: University of Zagreb, Faculty of Science, 2024. urn:nbn:hr:217:242514
Fašnik, Dora
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Fašnik, D. (2024). Uloga retinoične kiseline u diferencijaciji matičnih stanica sisavaca (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:242514

Fašnik, Dora. "Uloga retinoične kiseline u diferencijaciji matičnih stanica sisavaca." Undergraduate thesis, University of Zagreb, Faculty of Science, 2024. https://urn.nsk.hr/urn:nbn:hr:217:242514

Fašnik, Dora. "Uloga retinoične kiseline u diferencijaciji matičnih stanica sisavaca." Undergraduate thesis, University of Zagreb, Faculty of Science, 2024. https://urn.nsk.hr/urn:nbn:hr:217:242514

Fašnik, D. (2024). 'Uloga retinoične kiseline u diferencijaciji matičnih stanica sisavaca', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 28 December 2024, https://urn.nsk.hr/urn:nbn:hr:217:242514

Fašnik D. Uloga retinoične kiseline u diferencijaciji matičnih stanica sisavaca [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2024 [cited 2024 December 28] Available at: https://urn.nsk.hr/urn:nbn:hr:217:242514

D. Fašnik, "Uloga retinoične kiseline u diferencijaciji matičnih stanica sisavaca", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:217:242514

Metadata
TitleUloga retinoične kiseline u diferencijaciji matičnih stanica sisavaca
Title (english)The role of retinoic acid in mammalian stem cell differentiation
AuthorDora Fašnik
MentorRomana Gračan (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2024-07-12, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
U ovom su radu prikazana dosadašnja istraživanja i saznanja o učincima retinoične kiseline koji potiču diferencijaciju matičnih stanica kod sisavaca. Retinoična kiselina je morfogen koji ima širok raspon funkcija tijekom embrionalnog razvoja organizma. Na diferencijaciju matičnih stanica može djelovati na razini genoma ili preko izvangenomskih mehanizama. Također ima velik potencijal u primjeni u terapijske svrhe protiv teških i malignih bolesti. No poznat je i njen oprečni utjecaj na stimulaciju proliferacije stanica. Cilj ovog rada bio je obuhvatiti nove zaključke u ovom širokom području i otvoriti pitanja za buduća istraživanja ključna za bolje razumijevanje mehanizama retinoične kiseline i njene suradnje s drugim molekulama u staničnom mikrookolišu koje oblikuju staničnu sudbinu.
Abstract (english)
This paper presents the current research and findings on the effects of retinoic acid that promote the differentiation of stem cells in mammals. Retinoic acid is a morphogen with a wide range of functions during the embryonic development of an organism. It can influence stem cell differentiation at the genomic level or through non-genomic mechanisms. Additionally, it holds significant potential for therapeutic applications against severe and malignant diseases. However, its contradictory impact on the stimulation of cell proliferation is also well-known. The aim of this paper was to encompass new conclusions in this broad field and to raise questions for future research crucial for a better understanding of the mechanisms of retinoic acid and its interactions with other molecules in the cellular microenvironment that shape cell fate.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:242514
Study programmeTitle: Molecular biology-University undergraduate programme
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-09-03 12:47:44