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undergraduate thesis
Peroksisomi
Zagreb: University of Zagreb, Faculty of Science, 2024. urn:nbn:hr:217:815716
Mrkonja, Magdalena
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Mrkonja, M. (2024). Peroksisomi (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:815716

Mrkonja, Magdalena. "Peroksisomi." Undergraduate thesis, University of Zagreb, Faculty of Science, 2024. https://urn.nsk.hr/urn:nbn:hr:217:815716

Mrkonja, Magdalena. "Peroksisomi." Undergraduate thesis, University of Zagreb, Faculty of Science, 2024. https://urn.nsk.hr/urn:nbn:hr:217:815716

Mrkonja, M. (2024). 'Peroksisomi', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 12 March 2025, https://urn.nsk.hr/urn:nbn:hr:217:815716

Mrkonja M. Peroksisomi [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2024 [cited 2025 March 12] Available at: https://urn.nsk.hr/urn:nbn:hr:217:815716

M. Mrkonja, "Peroksisomi", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:217:815716

Metadata
TitlePeroksisomi
Title (english)Peroxisomes
AuthorMagdalena Mrkonja
MentorMaja Matulić (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2024-09-17, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Peroksisomi su kuglasti organeli prisutni u gotovo svim eukariotskim stanicama. Obavijeni su jednoslojnom membranom, nemaju vlastiti genetički materijal i osnovna im funkcija je oksidacija različitih supstrata. Glavne metaboličke uloge peroksisoma su β-oksidacija, detoksikacija reaktivnih kisikovih vrsta te glioksilatni ciklus i fotorespiracija u biljnim stanicama. Nastaju diobom postojećih peroksisoma, mehanizmom nalik mitohondrijskom ili de novo pupanjem vezikula s endoplazmatskog retikuluma.... More Za nastanak peroksisoma važni su proteini peroksini. Proteini peroksisoma sintetiziraju se na slobodnim ribosomima u stanici i unose se posttranslacijski kao smotani ili oligomerni proteini u matriks peroksisoma kroz privremenu poru koja nastaje na njihovoj membrani. Peroksini Pex5 i Pex7 služe kao topljivi receptori za unos proteina matriksa, a Pex19 služi kao receptor za ugradnju proteina membrane peroksisoma. Broj peroksisoma u stanici je reguliran i postoje mehanizmi koji kontroliraju nasljeđivanje peroksisoma. Peroksisomi se većinom degradiraju procesom peksofagije koja je regulirana ubikvitinacijom. Bolesti vezane u peroksisome mogu biti uzrokovane nedostatkom pojedinog enzima, primjerice X-vezana adrenoleukodistrofija ili nedostatkom funkcionalnih peroksisoma, primjerice Zellwegerov sindrom. Less
Abstract (english)
Peroxisomes are spherical organels present in almost all eukaryotic cells. They are enclosed in a single membrane, they do not have their own genetic material and their primary function is oxidation of different substrates. Key metabolic roles of peroxisomes are β-oxidation, detoxification of reactive oxygen species, and glyoxylate cycle and photorespiration in plant cells. Peroxisomes arise by division of existing peroxisomes by mechanism like that of mitochondria or by de novo biogenesis by... More budding of vesicles from endoplasmic reticulum. Peroxins are proteins important for peroxisomal biogenesis. Peroxisomal proteins are synthesized on free ribosomes in cells and are posttranslationally imported in folded or oligomeric shape through transient pore on peroxisomal membrane. Peroxins Pex5 and Pex7 are soluble receptors for matrix protein import and Pex19 is a receptor for import of peroxisomal membrane proteins. Number of peroxisomes in cells is regulated and there are mechanisms that direct inheritance of peroxisomes during cell division. Peroxisomes are mostly degraded by pexophagy which is mostly regulated by ubiquitination. Peroxisome disorders can be caused by a single enzyme deficiency, such as in X-linked adrenoleukodystrophy, or by absence of functional peroxisomes, such as in Zellweger syndrome. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:815716
Study programmeTitle: Molecular biology-University undergraduate programme
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-09-30 11:01:43
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