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doctoral thesis
Genetička raznolikost bakterija coxiella burnetii u Hrvatskoj
Zagreb: University of Zagreb, Faculty of Science, 2012. urn:nbn:hr:217:207256
Račić, Ivana
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Račić, I. (2012). Genetička raznolikost bakterija coxiella burnetii u Hrvatskoj (Doctoral thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:207256

Račić, Ivana. "Genetička raznolikost bakterija coxiella burnetii u Hrvatskoj." Doctoral thesis, University of Zagreb, Faculty of Science, 2012. https://urn.nsk.hr/urn:nbn:hr:217:207256

Račić, Ivana. "Genetička raznolikost bakterija coxiella burnetii u Hrvatskoj." Doctoral thesis, University of Zagreb, Faculty of Science, 2012. https://urn.nsk.hr/urn:nbn:hr:217:207256

Račić, I. (2012). 'Genetička raznolikost bakterija coxiella burnetii u Hrvatskoj', Doctoral thesis, University of Zagreb, Faculty of Science, accessed 04 December 2024, https://urn.nsk.hr/urn:nbn:hr:217:207256

Račić I. Genetička raznolikost bakterija coxiella burnetii u Hrvatskoj [Doctoral thesis]. Zagreb: University of Zagreb, Faculty of Science; 2012 [cited 2024 December 04] Available at: https://urn.nsk.hr/urn:nbn:hr:217:207256

I. Račić, "Genetička raznolikost bakterija coxiella burnetii u Hrvatskoj", Doctoral thesis, University of Zagreb, Faculty of Science, Zagreb, 2012. Available at: https://urn.nsk.hr/urn:nbn:hr:217:207256

Metadata
TitleGenetička raznolikost bakterija coxiella burnetii u Hrvatskoj
Title (english)Genetic diversity of bacteria coxiella burnetii in Croatia
AuthorIvana Račić
MentorSilvio Špičić (mentor)
MentorAna Galov (sumentor)
Committee memberJasna Hrenović (član povjerenstva)
Committee memberAna Galov (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2012, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Universal decimal classification
(UDC)		575 - General genetics. General cytogenetics
Abstract
Bakterijska vrsta Coxiella burnetii je vrlo infektivna bakterija i obvezatni unutarstanični parazit. U ljudi i životinja uzrokuje Q-groznicu koja je raširena po cijelom svijetu. U ovom radu su po prvi put genotipizirani sojevi vrste C. burnetii u Hrvatskoj metodom MLVA (Multi Locus VNTR Analysis, Variable Number of Tandem Repeats) koja se u svijetu tek uvodi kao metoda za genotipizaciju bakterije C. burnetii. Metoda je primijenjena na 49 uzoraka podrijetlom od domaćih životinja, 15 uzoraka je u potpunosti tipizirano, a njih 14 svrstano je u jedan od 10 dobivenih genotipova. Dva genotipa srodnija su s genotipovima u svijetu nego s hrvatskim genotipovima, a karakteristični su za kontinentalni dio Hrvatske. Ostali genotipovi srodniji su međusobno nego sa stranim genotipovima, a karakteristični su za primorski dio Hrvatske. Metoda MLVA uvedena je kao rutinski dijagnostički postupak čime je omogućeno utvrđivanje izvora i puteva širenja infekcije što će pridonijeti kontroli i suzbijanju bolesti u domaćih životinja koje su ujedno primarni izvor zaraze za ljude.
Abstract (english)
Coxiella burnetii is very infectious intracellular bacterium. In humans and animals it causes Q-fever which is spread all around the world. This study was the first time of genotyping C. burnetii strains in Croatia. The strains were genotyped using MLVA (Multi Locus VNTR Analysis, Variable Number of Tandem Repeats) method, a method recently introduced for the C. burnetii genotyping in the world. The 49 domestic animals' samples were genotyped, 15 samples were typed completely and 14 of them were assigned to one of 10 obtained genotypes. Two genotypes are more similar to the genotypes in the world than to other genotypes in Croatia and they are typical for continental part of Croatia. All other genotypes are more similar to each other than to foreign genotypes. These genotypes are typical for the coastal part of Croatia. The MLVA was implemented as tool for locating the source of the infection and the route of transmission which is essential in prevention and controlling the disease.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:207256
Study programmeTitle: Biology
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor/doktorica znanosti, područje prirodnih znanosti, polje biologija (doktor/doktorica znanosti, područje prirodnih znanosti, polje biologija)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Embargo expiration date: 2019-06-08
Terms of useLicence In copyright icon
Created on2017-06-08 10:16:56