prikaz prve stranice dokumenta Određivanje elementnih profila pripravaka ljekovitog bilja spektrometrijskim i kemometrijskim metodama
  Download
PDF 1.62 MB
master's thesis
Određivanje elementnih profila pripravaka ljekovitog bilja spektrometrijskim i kemometrijskim metodama
Zagreb: University of Zagreb, Faculty of Science, 2017. urn:nbn:hr:217:004938
Marciuš, Bernardo
University of Zagreb
Faculty of Science
Department of Chemistry

Institutional repository: Repository of the Faculty of Science

Cite this document

Marciuš, B. (2017). Određivanje elementnih profila pripravaka ljekovitog bilja spektrometrijskim i kemometrijskim metodama (Master's thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:004938

Marciuš, Bernardo. "Određivanje elementnih profila pripravaka ljekovitog bilja spektrometrijskim i kemometrijskim metodama." Master's thesis, University of Zagreb, Faculty of Science, 2017. https://urn.nsk.hr/urn:nbn:hr:217:004938

Marciuš, Bernardo. "Određivanje elementnih profila pripravaka ljekovitog bilja spektrometrijskim i kemometrijskim metodama." Master's thesis, University of Zagreb, Faculty of Science, 2017. https://urn.nsk.hr/urn:nbn:hr:217:004938

Marciuš, B. (2017). 'Određivanje elementnih profila pripravaka ljekovitog bilja spektrometrijskim i kemometrijskim metodama', Master's thesis, University of Zagreb, Faculty of Science, accessed 06 April 2025, https://urn.nsk.hr/urn:nbn:hr:217:004938

Marciuš B. Određivanje elementnih profila pripravaka ljekovitog bilja spektrometrijskim i kemometrijskim metodama [Master's thesis]. Zagreb: University of Zagreb, Faculty of Science; 2017 [cited 2025 April 06] Available at: https://urn.nsk.hr/urn:nbn:hr:217:004938

B. Marciuš, "Određivanje elementnih profila pripravaka ljekovitog bilja spektrometrijskim i kemometrijskim metodama", Master's thesis, University of Zagreb, Faculty of Science, Zagreb, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:217:004938

Metadata
TitleOdređivanje elementnih profila pripravaka ljekovitog bilja spektrometrijskim i kemometrijskim metodama
Title (english)Determination of elemental profile of herbal drugs using spectrometric and chemometric methods
AuthorBernardo Marciuš
MentorSanda Rončević (mentor)
Committee memberSanda Rončević (predsjednik povjerenstva)
Committee memberBiserka Prugovečki (član povjerenstva)
Committee memberIvan Kodrin (član povjerenstva)
Committee memberIva Juranović Cindrić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Science
(Department of Chemistry)
Zagreb
Defense date and country2017-09-21, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Određivanje esencijalnih, ne-esencijalnih i toksičnih elemenata u ljekovitom bilju i priravcima ljekovitog bilja vrlo je važno u procjeni nutritivnih vrijednosti, bioraspoloživosti te predviđanju negativnih posljedica na zdravlje čovjeka i okoliš. Odnedavno se primjenjuje novi postupak priprave suspenzija integralnih biljaka zvani liksiviacija tj. ekstrakcija u gradijentu etanola pri kriogenim uvjetima. Navedenim postupkom povećan je udio aktivnih prirodnih spojeva, no studije koje bi dale uvid... More u elementni sastav su nedostatne. Analitičke spektrometrijske metode temeljene na plazma izvoru omogućuju istodobno i precizno određovanje koncetracije metala u realnim uzorcima te uz različite kemometrijske metode omogućavaju interpretaciju elementnih profila koji su temelj prepoznavanja botaničkog i geografskog porijekla biljaka. U ovom radu određeni je elementni sastav standardiziranih ekstrakata ljekovitog bilja te dodataka prehrani izvedenih iz ljekovitih biljaka Ehinacea purpurea, Curcuma longa, Rhodiola rosea i Paullinia cupana metodom atomske emisijske spektrometrije uz induktivno spregnutu plazmu. Odabrane su emisijske linije koje nemaju značajne interferencije. Postignuta je vrlo dobra preciznost mjerenja (RSD < 2%). Linearnost linija bila je u zadovoljavajućem rasponu vrijednosti koeficijenata korelacije (R2 0,9995). Kontrola točnosti utvrđena je sa tri cerificirana referentna materijala. Elementi profil uzoraka izveden je iz mjerenih podataka upotrebom kemometrijskih alata, tj. univarijatne i multivarijatne statističke analize. Određivanjem elementnog profila standardiziranih ekstrakata ljekovitog bilja i dodataka prehrani dobiven je uvid u sadržaj elemenata: Ba, B, Ca, Cd, Co, Cr, Cu, Fe, K, Mn, Pb, Sr, V i Zn. Less
Abstract (english)
Determination of essential, non-essential and toxic elements in medicinal plants and herbal extracts is of great importance in evaluation of nutritional value and bioavailability, and in predicting the negative consequences on human health and on the environment. Lixiviation, a new procedure for preparation of medicinal herb suspension has been applied recently; i.e. extraction in ethanol gradient under cryogenic conditions. This procedure increased the amount of active natural compounds, but... More studies that would give insight into the elemental composition are insufficient. Analytical spectrometric method based on plasma source provide precise and simultaneous determination of metal concentrations in real samples. Processing of obtained data with chemometric methods allow interpretation of elemental profiles, which are generally, the fundamental in recognizing botanical and geographical origin. In this study, elemental profile of standardized herbal extracts and dietary supplements derived from herbal plants Ehinacea purpurea, Curcuma longa, Rhodiola rosea i Paullinia cupana was determined using inductively coupled plasma optical emission spectrometry. Emission lines that had no significant interferences were selected. Satisfying analytical precision was achieved. Accuracy of applied analytical procedures and samples was established in comparison with three certified reference materials. The elemental profile of the samples was derived from measured data sets using chemometric tools, univariate and multivariate statistical analysis. Elemental profiling of standardized herbal extracts and dietary supplements provided insight into elemental content of essential and trace elements. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:004938
Study programmeTitle: Graduate university studies in chemistry; specializations in: Research programme
Course: Research programme
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra kemije (magistar/magistra kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Embargo expiration date: 2019-09-21
Terms of useLicence In copyright icon
Created on2017-10-17 16:33:27
accessibility

closeAccessibilityrefresh

If you wish to permanently save changes, click on Save, if not - your settings will be reset when you restart the browser.