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undergraduate thesis
Posttranskripcijsko procesiranje primarnog transkripta za tRNA
Zagreb: University of Zagreb, Faculty of Science, 2016. urn:nbn:hr:217:408751
Čavka, Ivana
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Čavka, I. (2016). Posttranskripcijsko procesiranje primarnog transkripta za tRNA (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:408751

Čavka, Ivana. "Posttranskripcijsko procesiranje primarnog transkripta za tRNA." Undergraduate thesis, University of Zagreb, Faculty of Science, 2016. https://urn.nsk.hr/urn:nbn:hr:217:408751

Čavka, Ivana. "Posttranskripcijsko procesiranje primarnog transkripta za tRNA." Undergraduate thesis, University of Zagreb, Faculty of Science, 2016. https://urn.nsk.hr/urn:nbn:hr:217:408751

Čavka, I. (2016). 'Posttranskripcijsko procesiranje primarnog transkripta za tRNA', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 26 August 2024, https://urn.nsk.hr/urn:nbn:hr:217:408751

Čavka I. Posttranskripcijsko procesiranje primarnog transkripta za tRNA [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2016 [cited 2024 August 26] Available at: https://urn.nsk.hr/urn:nbn:hr:217:408751

I. Čavka, "Posttranskripcijsko procesiranje primarnog transkripta za tRNA", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:217:408751

Metadata
TitlePosttranskripcijsko procesiranje primarnog transkripta za tRNA
Title (english)Post-transcriptional processing of tRNA-precursor molecule
AuthorIvana Čavka
MentorJasmina Rokov Plavec (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2016, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Glavna tema ovog rada je procesiranje primarnog transkripta za tRNA. Molekule tRNA u stanici imaju veoma važne uloge. Osim njihove primarne uloge u translaciji, molekule tRNA sudjeluju i u staničnoj regulaciji i odgovoru stanice na stres. Funkcionalnost biomolekula je osigurana ispravnošću njihove konformacije, koja se stječe kroz različite procese sazrijevanja molekule. Molekule tRNA nisu iznimka od ovog pravila, pošto je ispravno obavljanje njihovih uloga od iznimne važnosti za normalno funkcioniranje stanice. Primarni transkripti uvelike se razlikuju od zrele, funkcionalne molekule tRNA i moraju proći kroz različite oblike posttranskripcijskog procesiranja kako bi sazreli. Ovo procesiranje kod većine organizama uključuje procesiranje krajeva, izrezivanje introna i uvođenje različitih modifikacija ribonukleotida. Rad nudi kratak uvod u svaki od ovih koraka uz navedene najbolje poznate primjere iz tri domene (Archaea, Bacteria, Eukaryota), a uz glavnu temu obrađene su i one usko povezane uz procesiranje poput raznolikosti gena za tRNA i putovanja molekula tRNA kroz eukariotsku stanicu tijekom biogeneze.
Abstract (english)
Main topic of this paper is post-transcriptional processing of tRNA precursor molecule. In a cell, tRNA molecules play a very important role. Except their well-known primary role in translation, tRNA molecules are also involved in processes such as stress response and different cellular regulation pathways. In order to properly play their roles in the cell, biomolecules have to be folded correctly. tRNAs are not exceptions to this rule, since maintenance of processes that involve tRNA molecules is crucial for cell’s viability. tRNA precursor molecules differ substantially from the mature tRNAs and, in order to become functional molecules, they have to undergo post-transcriptional processing. Processing mainly involves end processing, splicing, and ribonucleotide modifications. Paper offers a short introduction to each step with best known examples from all three domains of life (Archaea, Bacteria, Eukaryota). Except for the post-transcriptional processing, some closely related topics, such as diversity of tRNA genes and tRNA subcellular trafficking in eukaryotic cells, are also discussed.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:408751
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-01-02 08:24:52