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undergraduate thesis
Metode sekvenciranja novih generacija u dijagnostici
Zagreb: University of Zagreb, Faculty of Science, 2016. urn:nbn:hr:217:027412
Kaltak, Melita
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

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Kaltak, M. (2016). Metode sekvenciranja novih generacija u dijagnostici (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:027412

Kaltak, Melita. "Metode sekvenciranja novih generacija u dijagnostici." Undergraduate thesis, University of Zagreb, Faculty of Science, 2016. https://urn.nsk.hr/urn:nbn:hr:217:027412

Kaltak, Melita. "Metode sekvenciranja novih generacija u dijagnostici." Undergraduate thesis, University of Zagreb, Faculty of Science, 2016. https://urn.nsk.hr/urn:nbn:hr:217:027412

Kaltak, M. (2016). 'Metode sekvenciranja novih generacija u dijagnostici', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 04 November 2024, https://urn.nsk.hr/urn:nbn:hr:217:027412

Kaltak M. Metode sekvenciranja novih generacija u dijagnostici [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2016 [cited 2024 November 04] Available at: https://urn.nsk.hr/urn:nbn:hr:217:027412

M. Kaltak, "Metode sekvenciranja novih generacija u dijagnostici", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:217:027412

Metadata
TitleMetode sekvenciranja novih generacija u dijagnostici
Title (english)Next generation sequencing in diagnostic
AuthorMelita Kaltak
MentorPetra Korać (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2016, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Metode sekvenciranja novih generacija su najznačajnije otkriće u znanosti biologije u proteklih 40 godina. Nakon Sangerove metode koju nazivamo metodom sekvenciranja prve generacije, razvijaju se metode druge i treće generacije sekvenciranja. Metode sekvenciranja novih generacija daju rezultate u sve kraćem vremenskom periodu te su svakim danom sve učinkovitije. Danas je moguće sekvencirati tisuće i tisuće genoma spomenutim metodama, što omogućava otvaranje mnogih puteva u raznim područjima znanosti i uvelike pridonosi kvaliteti života. Ove metode su veoma značajne u području dijagnostike, tako što omogućuju brže i učinkovitije otkriće raznih kromosomskih nepravilnosti koje dovode do nasljednih bolesti, čestih bolesti u nekoj populaciji te malignih tumora. U ovom radu izložen je kratak povijesni pregled razvoja raznih metoda sekvenciranja kroz zadnja desetljeća , njihova uporaba u raznim područjima, ponajviše njihov doprinos u kliničkim laboratorijima i predstavljanje tih metoda kao novog alata u otkrivanju uzroka mnogih bolesti.
Abstract (english)
New generation-sequencing methods are the most important discovery in biology in the past 40 years. After Sanger sequencing, which is also called the first-generation sequencing, the second and the third-generation sequencing are developed. The new-generation sequencing methods are showing results in shorter time periods and are getting more efficient day by day. Today it is possible to sequence thousands and thousands of genoms with these methods, and this opens many pathways in many areas of science and contribute to the quality lives. These methods are highly significant in many fields of diagnostics, because they help to determine chromosomes irregularities, which cause hereditary diseases, common diseases in a population, and malignant tumors faster and more efficient. This work presents a short historical overview of the development of various sequencing methods through the last decade , their use in various fields , particularly their contribution to clinical laboratories and presentation of these methods as a new tool in detecting causes of many diseases.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:027412
Study programmeTitle: Ecology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-01-03 08:26:58