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undergraduate thesis
Kronično zatajenje bubrega i prilagodbe na hibernaciju kod sisavaca
Zagreb: University of Zagreb, Faculty of Science, 2016. urn:nbn:hr:217:679117
Trupinić, Monika
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Trupinić, M. (2016). Kronično zatajenje bubrega i prilagodbe na hibernaciju kod sisavaca (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:679117

Trupinić, Monika. "Kronično zatajenje bubrega i prilagodbe na hibernaciju kod sisavaca." Undergraduate thesis, University of Zagreb, Faculty of Science, 2016. https://urn.nsk.hr/urn:nbn:hr:217:679117

Trupinić, Monika. "Kronično zatajenje bubrega i prilagodbe na hibernaciju kod sisavaca." Undergraduate thesis, University of Zagreb, Faculty of Science, 2016. https://urn.nsk.hr/urn:nbn:hr:217:679117

Trupinić, M. (2016). 'Kronično zatajenje bubrega i prilagodbe na hibernaciju kod sisavaca', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 25 November 2024, https://urn.nsk.hr/urn:nbn:hr:217:679117

Trupinić M. Kronično zatajenje bubrega i prilagodbe na hibernaciju kod sisavaca [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2016 [cited 2024 November 25] Available at: https://urn.nsk.hr/urn:nbn:hr:217:679117

M. Trupinić, "Kronično zatajenje bubrega i prilagodbe na hibernaciju kod sisavaca", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2016. Available at: https://urn.nsk.hr/urn:nbn:hr:217:679117

Metadata
TitleKronično zatajenje bubrega i prilagodbe na hibernaciju kod sisavaca
Title (english)Chronic kidney failure and mammalian adaptations during hibernation
AuthorMonika Trupinić
MentorDuje Lisičić (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2016, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
S rastućom ljudskom populacijom, raste broj bolesti koje bitno smanjuju kvalitetu života. Kronične bolesti bubrega spadaju u jedne od najraširenijih bolesti ljudi za koje nemamo trajno rješenje. Do toga mogu dovesti različiti uzročnici, a velika poveznica vidi se s pretilošću koja često dovodi do hipertenzije i dijabetesa. Bubrezi, kao organi koji održavaju homeostazu cjelokupnog organizma, nisu zamjenjivi i svaka nepravilnost u radu postaje alarmantna. Mnoge današnje metode liječenja pomažu u održavanju normalnog stanja organizma tamo gdje bubreg više ne može, međutim takve terapije su iscrpne i potrebno ih je konstantno ponavljati. Jedno od mogućih rješenja u budućem liječenju bolesti bubrega znanstvenici su vidjeli u prirodi. Životinje u stanju hibernacije ne unose hranu, vodu, ne kreću se i ne izbacuju fekalije, međutim njihov organizam ostaje funkcionalan i bez posljedica. Najzanimljiviji su medvjedi koji imaju jedinstvenu sposobnost recikliranja ureje, stvarajući proteine. Ako bismo otkrili na koji način, tj. koji geni i mehanizmi su uključeni u taj proces, mogli bismo to iskoristiti u liječenju pacijenata koji više nemaju funkcionalne bubrege.
Abstract (english)
With growing human population, we can also see growth in the number of diseases that influence the quality of life. Chronic kidney diseases are one of the most common human diseases that we can't permanently cure. Various causes may lead to chronic kidney disease but there is visible correlation with obesity which often leads to hypertension and diabetes. Kidneys, as organs who are greatly responsible for body homeostasis, are not replaceable and every malfunction is alarming. Modern medicine and therapies help to keep normal bodily functions in departments that kidneys are not capable anymore, but those treatments are often exhausting for patients and need to be repeated constantly. One possible solution in future treatments of kidney diseases can find its inspiration in nature. Hibernating animals don't eat, drink, move or urinate, and are still completely healthy without any conseqences. The most interesting animals are bears with their unique ability to recycle urea into proteins. If we can determine genes and mechanisms involved in this process, maybe we could use it in future treatments of patients whose kidneys have failed.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:679117
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-01-04 11:02:25