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undergraduate thesis
Topologija nukleosoma u kromatinskoj strukturi
Zagreb: University of Zagreb, Faculty of Science, 2009. urn:nbn:hr:217:174427
Vučković, Frano
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

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Vučković, F. (2009). Topologija nukleosoma u kromatinskoj strukturi (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:174427

Vučković, Frano. "Topologija nukleosoma u kromatinskoj strukturi." Undergraduate thesis, University of Zagreb, Faculty of Science, 2009. https://urn.nsk.hr/urn:nbn:hr:217:174427

Vučković, Frano. "Topologija nukleosoma u kromatinskoj strukturi." Undergraduate thesis, University of Zagreb, Faculty of Science, 2009. https://urn.nsk.hr/urn:nbn:hr:217:174427

Vučković, F. (2009). 'Topologija nukleosoma u kromatinskoj strukturi', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 27 December 2024, https://urn.nsk.hr/urn:nbn:hr:217:174427

Vučković F. Topologija nukleosoma u kromatinskoj strukturi [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2009 [cited 2024 December 27] Available at: https://urn.nsk.hr/urn:nbn:hr:217:174427

F. Vučković, "Topologija nukleosoma u kromatinskoj strukturi", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2009. Available at: https://urn.nsk.hr/urn:nbn:hr:217:174427

Metadata
TitleTopologija nukleosoma u kromatinskoj strukturi
Title (english)Topology of nucleosomes in chromatin structure
AuthorFrano Vučković
MentorVišnja Besendorfer (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2009, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
DNA u eukariotskih kromosoma organizirana je u nukleosome, strukture građene od proteina i DNA, koje predstavljaju osnovnu građevnu i funkcionalnu jedinicu kromosomskog materijala, kromatina. Smatanjem niza nukleosoma nastaje viša razina strukture, kromatinska nit debljine 30 nm. I dok se o strukturi nukleosoma danas praktički sve zna, o 30 nm-niti ali i o višim razinama strukture kromatina još se uvijek malo zna. U ovom radu izloženi su modeli koji pokušavaju objasniti strukturu kromatinske niti: solenoidni model, model zavijene vrpce, dvopočetni ukriženi model te nesekvencijski jednopočetni model, sa razlikom u putu koji prelazi DNA između dva nukleosoma. Razumijevanje strukture 30 nm-niti od izuzetne je važnosti za shvaćanje regulacije procesa transkripcije, rekombinacije, DNA popravka te replikacije.
Abstract (english)
DNA in eukaryotic chromosomes is organized in the nucleosomes, structures which contain proteins and DNA, and which represent elementary structural and functional unit of chromosomal material, chromatin. Arrays of nucleosomes are folded into higher order structure, 30 nm chromatin fiber. Although the structure of nucleosome is known in smallest detail, only a few facts are known about 30 nm fibre and higher chromatin structures. In this work, I exposed models for structure of 30 nm chromatin fibers: solenoid, twisted-ribbon, two-started crossed-linker and one-started nonsequential model, with difference in the path of DNA between two nucleosomes. Uncovering of 30 nm fibre structure is crucial for understanding the regulation of processes such as transcription, recombination, DNA repair and replication.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:174427
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2018-03-20 12:48:49