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undergraduate thesis
Učinak retinoične kiseline na embrionalni razvoj sisavaca
Zagreb: University of Zagreb, Faculty of Science, 2009. urn:nbn:hr:217:670860
Žalac, Sanja
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Žalac, S. (2009). Učinak retinoične kiseline na embrionalni razvoj sisavaca (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:670860

Žalac, Sanja. "Učinak retinoične kiseline na embrionalni razvoj sisavaca." Undergraduate thesis, University of Zagreb, Faculty of Science, 2009. https://urn.nsk.hr/urn:nbn:hr:217:670860

Žalac, Sanja. "Učinak retinoične kiseline na embrionalni razvoj sisavaca." Undergraduate thesis, University of Zagreb, Faculty of Science, 2009. https://urn.nsk.hr/urn:nbn:hr:217:670860

Žalac, S. (2009). 'Učinak retinoične kiseline na embrionalni razvoj sisavaca', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 25 November 2024, https://urn.nsk.hr/urn:nbn:hr:217:670860

Žalac S. Učinak retinoične kiseline na embrionalni razvoj sisavaca [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2009 [cited 2024 November 25] Available at: https://urn.nsk.hr/urn:nbn:hr:217:670860

S. Žalac, "Učinak retinoične kiseline na embrionalni razvoj sisavaca", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2009. Available at: https://urn.nsk.hr/urn:nbn:hr:217:670860

Metadata
TitleUčinak retinoične kiseline na embrionalni razvoj sisavaca
Title (english)Impact of retinoic acid on embryonic development of mammals
AuthorSanja Žalac
MentorGordana Lacković-Venturin (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2009, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Normalna morfogeneza embrija kralježnjaka je pod velikim utjecajem vanjskih doza retinoične kiseline. Uobičajeno, dovodi do kraniofacijalnih abnormalnosti i defekata srca te do deformacije udova. RA interferira s specifikacijom osnovice ektoderma i mezoderma tokom gastrulacije. Udovi u razvoju osjetljivi su i na manjak i na višak RA. Genetičke i biokemijske manipulacije pokazuju da su retinoidi neophodni za razvoj udova vertebrata u dva stadija: u ranoj organogenezi za začetak razvoja prednjih udova, te u srednjoj organogenezi za rast udova.
Abstract (english)
Normal morphogenesis of vertebrate embryos is severely affected by externally doses of retinoic acid. Typically it leads to craniofacial abnormalities and heart defects and to limb deformities. Limbs in development are sensitive to deficiency and excess of RA. Genetic and biochemical manipulations indicate that retinoids are crucial for vertebate limb development at two stages, in early organogenesis for forelimb bud initiation, and later in mid-organogenesis, for proper limb outgrowth.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:670860
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-03-21 13:00:20