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undergraduate thesis
Upotreba zmijskih toksina u medicini
Zagreb: University of Zagreb, Faculty of Science, 2010. urn:nbn:hr:217:368194
Mavrović, Martina
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Mavrović, M. (2010). Upotreba zmijskih toksina u medicini (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:368194

Mavrović, Martina. "Upotreba zmijskih toksina u medicini." Undergraduate thesis, University of Zagreb, Faculty of Science, 2010. https://urn.nsk.hr/urn:nbn:hr:217:368194

Mavrović, Martina. "Upotreba zmijskih toksina u medicini." Undergraduate thesis, University of Zagreb, Faculty of Science, 2010. https://urn.nsk.hr/urn:nbn:hr:217:368194

Mavrović, M. (2010). 'Upotreba zmijskih toksina u medicini', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 22 November 2024, https://urn.nsk.hr/urn:nbn:hr:217:368194

Mavrović M. Upotreba zmijskih toksina u medicini [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2010 [cited 2024 November 22] Available at: https://urn.nsk.hr/urn:nbn:hr:217:368194

M. Mavrović, "Upotreba zmijskih toksina u medicini", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2010. Available at: https://urn.nsk.hr/urn:nbn:hr:217:368194

Metadata
TitleUpotreba zmijskih toksina u medicini
Title (english)The use of snake venom toxins in medicine
AuthorMartina Mavrović
MentorZoran Tadić (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2010, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Zmije se unutar skupine gmazova počinju odvajati u Kredi (geološko razdoblje Mezozoika koje je trajalo od prije 136 do pred 65 milijuna godina). Mogućnost stvaranja otrova razvijaju tokom Miocena (geološko razdoblje Neogena koje je trajalo od prije 23.03 do prije 5.33 milijuna godina). Prije stotinjak godina je dokazano da je moguće imunizirati životinju protiv zmijskog otrova i učiniti je otpornom na njega. Time je počela era moderne protuotrovne seroterapije, kao i drugih medicinskih upotreba toksina iz zmijskog otrova. Brojni lijekovi već sintetizirani na temelju toksina iz otrova zmija, mnogi se istražuju. Toksini su zanimljivi u proizvodnji lijekova jer pružaju trodimenzionalni predložak za kreiranje malenih molekula koje mogu oponašati djelovanje samog toksina. Izoliranje i proučavanje pojedinih komponenata zmijskog otrova utrli su put ka boljem razumijevanju patofiziologije trovanja, a time i pridonijeli poboljšanju liječenja raznih bolesti.
Abstract (english)
Snakes have started to diverge from the reptiles in Cretaceus (a geologic era of the Mesosoic which lasted form 136 million years ago untill 65 million years ago). They have developed the possibility of producing venom in Miocene (a geologic era of the Neogene, which lasted from 23.03 million years ago untill 5.33 million years ago). One hundred years ago it was proved possible to immunise an animal against snake venom, and make it resistant to the venom. With that event started the era of modern serotherapy, as well as other medicinal uses of snake venom toxins. Numerous drugs have already been synthetised based on toxins from snake venom, and numerous are still under research. Toxins are of interest in drug design because they provide a three-dimensional templade for the creation of small molecules which can mimic the effects of the toxin. The isolation and study of snake venom components has paved the way for a deeper understanding of the pathophisiology of envenomings, as well as opened a possibility to improve therapeutic modalities.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:368194
Study programmeTitle: Ecology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-03-28 10:46:07