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undergraduate thesis
Poremećaji u razvoju životinja izazvani kemijskim spojevima sličnim hormonima
Zagreb: University of Zagreb, Faculty of Science, 2010. urn:nbn:hr:217:945228
Nanić, Lucia
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Nanić, L. (2010). Poremećaji u razvoju životinja izazvani kemijskim spojevima sličnim hormonima (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:945228

Nanić, Lucia. "Poremećaji u razvoju životinja izazvani kemijskim spojevima sličnim hormonima." Undergraduate thesis, University of Zagreb, Faculty of Science, 2010. https://urn.nsk.hr/urn:nbn:hr:217:945228

Nanić, Lucia. "Poremećaji u razvoju životinja izazvani kemijskim spojevima sličnim hormonima." Undergraduate thesis, University of Zagreb, Faculty of Science, 2010. https://urn.nsk.hr/urn:nbn:hr:217:945228

Nanić, L. (2010). 'Poremećaji u razvoju životinja izazvani kemijskim spojevima sličnim hormonima', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 03 January 2025, https://urn.nsk.hr/urn:nbn:hr:217:945228

Nanić L. Poremećaji u razvoju životinja izazvani kemijskim spojevima sličnim hormonima [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2010 [cited 2025 January 03] Available at: https://urn.nsk.hr/urn:nbn:hr:217:945228

L. Nanić, "Poremećaji u razvoju životinja izazvani kemijskim spojevima sličnim hormonima", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2010. Available at: https://urn.nsk.hr/urn:nbn:hr:217:945228

Metadata
TitlePoremećaji u razvoju životinja izazvani kemijskim spojevima sličnim hormonima
Title (english)Disorders in animal development caused by endocrine disruptive chemicals
AuthorLucia Nanić
MentorGordana Lacković-Venturin (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2010, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Okolišni modulator signalnih molekula (EDC) definira se kao egzogeni kemijski spoj ili smjesa koja mijenja strukturu ili funkciju endokrinog sustava i uzrokuje različite posljedice na razini organizma, njegovog potomstva i populacija organizama. Spojevi nalik hormonima mogu narušiti endokrine signalne puteve koji igraju bitnu ulogu tijekom perinatalne diferencijacije i rezultirati promjenama koje postaju vidljive tek u kasnijim fazama života. Neki od tih spojeva, kao što su oralni kontraceptivi i cijeli niz pesticida, su specifično razvijeni da ciljaju endokrini sustav, ali velika većina tih spojeva nije bila dizajnirana ni namijenjena tome, pogotovo kod sisavaca. Neki spojevi, kao što je DDT, su sintetizirani za ubijanje komaraca i drugih štetočina koji šire ozbiljne i u nekim slučajevima po život opasne bolesti kao što je malarija. Drugi su razvijeni za usporavanje širenja vatre, za uništavanje korova ili da učine plastiku čvršćom, čišćom i otpornijom na toplinu (bisfenol A) ili savitljivijom (ftalati). Spojevi nastali u prirodi češće nego ljudskom djelatnošću, kao što su fitoestrogeni, također odgovaraju definiciji. Dokazi povezuju izloženost okolišnim spojevima nalik hormonima sa rastućom listom zdravstvenih problema.
Abstract (english)
An endocrine disruptor (EDC) is defined as an exogenous chemical substance or mixture that alters the structure or function of the endocrine system and causes adverse effects at the level of the organism, its progeny, and populations of organisms. Compounds with hormone-like activity can disrupt endocrine signaling pathways that play important roles during perinatal differentiation and result in alterations that are not apparent until later in life. Some of these compounds, such as oral contraceptives and a subset of pesticides, were specifically developed to target the endocrine system but the vast majority of these chemicals were neither designed nor intended to, especially in mammals. Some, such as DDT, were developed to kill mosquitoes and other pests that spread serious and in some cases life threatening human diseases such as malaria. Others were devised as flame retardants, to kill weeds, or to make plastics harder, clearer, and more resistant to heat stress (bisphenol A) or more pliable (the phthalates). Compounds produced in nature rather than by humans, such as the phytoestrogens (genistein), also fit this definition. Evidence implicates developmental exposure to environmental hormone-mimics with a growing list of health problems.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:945228
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2018-03-28 12:08:30