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undergraduate thesis
Metoda RAPD i njena primjena u istraživanju genotoksičnosti i karcinogeneze
Zagreb: University of Zagreb, Faculty of Science, 2012. urn:nbn:hr:217:269980
Ćosić, Marija
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Ćosić, M. (2012). Metoda RAPD i njena primjena u istraživanju genotoksičnosti i karcinogeneze (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:269980

Ćosić, Marija. "Metoda RAPD i njena primjena u istraživanju genotoksičnosti i karcinogeneze." Undergraduate thesis, University of Zagreb, Faculty of Science, 2012. https://urn.nsk.hr/urn:nbn:hr:217:269980

Ćosić, Marija. "Metoda RAPD i njena primjena u istraživanju genotoksičnosti i karcinogeneze." Undergraduate thesis, University of Zagreb, Faculty of Science, 2012. https://urn.nsk.hr/urn:nbn:hr:217:269980

Ćosić, M. (2012). 'Metoda RAPD i njena primjena u istraživanju genotoksičnosti i karcinogeneze', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 25 November 2024, https://urn.nsk.hr/urn:nbn:hr:217:269980

Ćosić M. Metoda RAPD i njena primjena u istraživanju genotoksičnosti i karcinogeneze [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2012 [cited 2024 November 25] Available at: https://urn.nsk.hr/urn:nbn:hr:217:269980

M. Ćosić, "Metoda RAPD i njena primjena u istraživanju genotoksičnosti i karcinogeneze", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2012. Available at: https://urn.nsk.hr/urn:nbn:hr:217:269980

Metadata
TitleMetoda RAPD i njena primjena u istraživanju genotoksičnosti i karcinogeneze
Title (english)The RAPD method and its application in studies of genotoxicity and carcinogenesis
AuthorMarija Ćosić
MentorMirjana Pavlica (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2012, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
S ciljem detekcije oštećenja genoma uzrokovanog štetnim tvarima iz okoliša razvijene su mnoge metode koje omogućuju brzi pregled molekule DNA izloženih organizama. Među njima je i metoda RAPD (engl. random amplified polymorphic DNA), koja se često koristi jer je jednostavna, učinkovita i brza. Osim u istraživanjima genotoksičnosti, metoda RAPD se koristi i u proučavanju karcinogeneze i populacijsko-genetičkim istraživanjima. U ovom radu su prikazane osnovne karakteristike metode RAPD i navedena su polja njezine primjene. Prikazani su nedostaci metode i načini na koje se može poboljšati, kao i usporedba te metode sa ostalim metodama koje se danas koriste. Nakon neophodne optimizacije, ova metoda je siguran i točan pokazatelj promjena u genomu, a u kombinaciji s drugim metodama daje jasan uvid u molekularno-genetička zbivanja.
Abstract (english)
In order to detect genome damage caused by harmful substances from the environment, many methods which enable fast overview of the DNA molecules of exposed organisms have been developed. Among them is the RAPD (random amplified polymorphic DNA) method, which is used frequently because it is simple, efficient and quick. Apart from genome-toxicity related research, RAPD is also used in the study of carcinogenesis and in the populationgenetic studies. The main characteristics of the RAPD method and the areas of its application were specified in this paper. The disadvantages of the method and the ways of its improvement were shown, along with the comparison of the method with other methods used nowadays. After the necessary optimization, this method could be safe and precise indicator of the genome changes , and combined with other methods it gives a clear insight into moleculargenetic events.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:269980
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-04-19 12:14:11