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doctoral thesis
Genomika i molekularna epidemiologija virusa iz porodica Paramyxoviridae i Pneumoviridae u Hrvatskoj
Zagreb: University of Zagreb, Faculty of Science, 2018. urn:nbn:hr:217:260179
Slović, Anamarija
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

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Slović, A. (2018). Genomika i molekularna epidemiologija virusa iz porodica Paramyxoviridae i Pneumoviridae u Hrvatskoj (Doctoral thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:260179

Slović, Anamarija. "Genomika i molekularna epidemiologija virusa iz porodica Paramyxoviridae i Pneumoviridae u Hrvatskoj." Doctoral thesis, University of Zagreb, Faculty of Science, 2018. https://urn.nsk.hr/urn:nbn:hr:217:260179

Slović, Anamarija. "Genomika i molekularna epidemiologija virusa iz porodica Paramyxoviridae i Pneumoviridae u Hrvatskoj." Doctoral thesis, University of Zagreb, Faculty of Science, 2018. https://urn.nsk.hr/urn:nbn:hr:217:260179

Slović, A. (2018). 'Genomika i molekularna epidemiologija virusa iz porodica Paramyxoviridae i Pneumoviridae u Hrvatskoj', Doctoral thesis, University of Zagreb, Faculty of Science, accessed 12 May 2024, https://urn.nsk.hr/urn:nbn:hr:217:260179

Slović A. Genomika i molekularna epidemiologija virusa iz porodica Paramyxoviridae i Pneumoviridae u Hrvatskoj [Doctoral thesis]. Zagreb: University of Zagreb, Faculty of Science; 2018 [cited 2024 May 12] Available at: https://urn.nsk.hr/urn:nbn:hr:217:260179

A. Slović, "Genomika i molekularna epidemiologija virusa iz porodica Paramyxoviridae i Pneumoviridae u Hrvatskoj", Doctoral thesis, University of Zagreb, Faculty of Science, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:217:260179

Metadata
TitleGenomika i molekularna epidemiologija virusa iz porodica Paramyxoviridae i Pneumoviridae u Hrvatskoj
Title (english)Genomics and molecular epidemiology of Paramyxoviruses and Pneumoviruses in croatia
AuthorAnamarija Slović
MentorDubravko Forčić (mentor)
Committee memberDijana Škorić (predsjednik povjerenstva)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2018, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Universal decimal classification
(UDC)		578/579 - Virology. Microbiology
Abstract
Porodice Paramyxoviridae i Pneumoviridae obuhvaćaju širok raspon virusnih patogena od kojih mnogi imaju utjecaj na ljudsko zdravlje. Najčešći uzročnici bolesti kod male djece iz ovih porodica su ljudski virusi parainfluence (eng. Human parainfluenza viruses, HPIV), te ljudski respiratorni sincicijski virus (eng. Human respiratory syncytial virus, HRSV) i ljudski metapneumovirus (eng. Human metapneumovirus, HMPV). U ovom istraživanju ispitana je molekularna evolucija HPIV, HRSV i HMPV virusa na području Zagreba tijekom nekoliko uzastopnih godina (2011.-2016.), koji su odgovorni za akutne respiratorne bolesti u pedijatrijskoj populaciji. Spoznaje o odnosima između postojećih genotipova na određenom području važne su za predviđanje epidemija te omogućavaju pravovremenu kontrolu širenja, što je od posebne važnosti za navedene viruse, s obzirom da ne postoji specifični antivirusni tretman niti cjepivo protiv ovih virusa. Molekularno-epidemiološkim analizama utvrđeno je postojanje velikog broja različitih virusnih sojeva, a rezultati ove studije doprinose poznavanju obrazaca cirkulacije ovih virusa kao i boljem razumijevanju molekularne epidemiologije.
Abstract (english)
The families Paramyxoviridae and Pneumoviridae comprise broad spectrum of viral pathogens, many of which affect human health. The most common causatives of infections in pediatric population from these families include Human parainfluenza viruses (HPIV), Human respiratory syncytial virus (HRSV) and Human metapneumovirus (HMPV). In this study, molecular evolution of HPIV, HRSV and HMPV viruses responsible for acute respiratory infections in Zageb region during several subsequent years (2011-2016) was investigated. The knowledge of current relations between existing viral genotypes in a particular region enables better predictions of future epidemics and facilitates viral control, which is especially important as there is no vaccine or treatment available for these viruses. Molecular epidemiological analyses revealed circulation of numerous different viral strains. Therefore, the results of this study contribute to a better understanding of circulation patterns and molecular epidemiology of these viruses.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:260179
Study programmeTitle: Biology
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor/doktorica znanosti, područje prirodnih znanosti, polje biologija (doktor/doktorica znanosti, područje prirodnih znanosti, polje biologija)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-07-11 11:17:58