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master's thesis
Ureidni bis-katekolni analog siderofora - sinteza i termodinamika kompleksiranja željezova(III) kationa
Zagreb: University of Zagreb, Faculty of Science, 2018. urn:nbn:hr:217:083105
Kalebić, Demian
University of Zagreb
Faculty of Science
Department of Chemistry

Institutional repository: Repository of the Faculty of Science

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Kalebić, D. (2018). Ureidni bis-katekolni analog siderofora - sinteza i termodinamika kompleksiranja željezova(III) kationa (Master's thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:083105

Kalebić, Demian. "Ureidni bis-katekolni analog siderofora - sinteza i termodinamika kompleksiranja željezova(III) kationa." Master's thesis, University of Zagreb, Faculty of Science, 2018. https://urn.nsk.hr/urn:nbn:hr:217:083105

Kalebić, Demian. "Ureidni bis-katekolni analog siderofora - sinteza i termodinamika kompleksiranja željezova(III) kationa." Master's thesis, University of Zagreb, Faculty of Science, 2018. https://urn.nsk.hr/urn:nbn:hr:217:083105

Kalebić, D. (2018). 'Ureidni bis-katekolni analog siderofora - sinteza i termodinamika kompleksiranja željezova(III) kationa', Master's thesis, University of Zagreb, Faculty of Science, accessed 20 November 2024, https://urn.nsk.hr/urn:nbn:hr:217:083105

Kalebić D. Ureidni bis-katekolni analog siderofora - sinteza i termodinamika kompleksiranja željezova(III) kationa [Master's thesis]. Zagreb: University of Zagreb, Faculty of Science; 2018 [cited 2024 November 20] Available at: https://urn.nsk.hr/urn:nbn:hr:217:083105

D. Kalebić, "Ureidni bis-katekolni analog siderofora - sinteza i termodinamika kompleksiranja željezova(III) kationa", Master's thesis, University of Zagreb, Faculty of Science, Zagreb, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:217:083105

Metadata
TitleUreidni bis-katekolni analog siderofora - sinteza i termodinamika kompleksiranja željezova(III) kationa
Title (english)Bis-Catechole Siderofore Analogue Containing Urea Moiety - Synthesis and Thermodynamics of Iron(III) Complexation
AuthorDemian Kalebić
MentorNikola Bregović (mentor)
MentorVesna Petrović Peroković (mentor)
Committee memberNikola Bregović (predsjednik povjerenstva)
Committee memberVesna Petrović Peroković (član povjerenstva)
Committee memberIva Juranović Cindrić (član povjerenstva)
Committee memberVladimir Stilinović (član povjerenstva)
Committee memberVladislav Tomišić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Science
(Department of Chemistry)
Zagreb
Defense date and country2018-09-28, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
U okviru ovog rada pripravljen je analog siderofora s dvije katekolne podjedinice i ureidnom poveznicom (LH4) te su istražena njegova kompleksacijska svojstva, odnosno afinitet za vezanje željezovih(III) kationa u vodenom mediju. Kombinacijom potenciometrijskih i spektrofotometrijskih mjerenja određene su protonacijske konstante ravnoteže LH4 i konstante stabilnosti kompleksa s Fe(III). Kako bi se pouzdano odredila stehiometrija svih nastalih željezovih kompleksa provedene su potenciometrijsko-spektrofotometrijske titracije pri nekoliko omjera koncentracija liganda i Fe(III). Prikupljeni rezultati pridonijet će boljem razumijevanju katekolnih receptora općenito, budući da je vrlo malen broj sličnih bis-katekolnih spojeva opisan u literaturi te je u ovom radu korištena specifična metodologija za potpunu karakterizaciju ravnotežnih reakcija kompleksiranja. Pripravljeni spoj uz katekolne skupine sadrži i ureidnu podjedinicu koja se često koristi kao anionsko vezno mjesto te će se u nastavku istraživanja proučiti mogućnosti vezanja ionskih parova s LH4, pri čemu će rezultati ovog rada biti od ključne važnosti.
Abstract (english)
In the scope of this thesis, the synthesis of a siderophore analogue bearing two catecholate subunits connected with an urea-based linker (LH4) was performed. This was followed by the study of its affinity for binding iron(III) cations in aqueous medium. The research included measurement of the LH4 protonation equilibrium constants, elucidation of the stoichiometry of the formed complexes and determination of the corresponding stability constants using potenctiometric and spectrophotometric measurments. This study will allow better understanting of catecholate receptors in general, since very few similar bis-catecholate receptors have been previously decribed, and the specific methodological approach applied in this work was proven to be advantageous for complete characterisation of complexation equilibria. In addition to catechol subunits, the studied receptor contains urea moiety, which possibly enables LH4 to act as ion-pair receptor. The data gathered in this work will greatly facilitate the study of its potential to simultaneously bind anions and iron(III) cation.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:083105
Study programmeTitle: Graduate university studies in chemistry; specializations in: Research programme
Course: Research programme
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra kemije (magistar/magistra kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Embargo expiration date: 2020-09-28
Terms of useLicence In copyright icon
Created on2018-11-23 11:30:23