prikaz prve stranice dokumenta Development of fractionation procedures for comprehensive characterization of organic contaminants in surface waters using effect-directed analyses
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doctoral thesis
Development of fractionation procedures for comprehensive characterization of organic contaminants in surface waters using effect-directed analyses
Zagreb: University of Zagreb, Faculty of Science, 2019. urn:nbn:hr:217:083275
Bačić, Sanja
University of Zagreb
Faculty of Science
Department of Chemistry

Institutional repository: Repository of the Faculty of Science

Cite this document

Bačić, S. (2019). Development of fractionation procedures for comprehensive characterization of organic contaminants in surface waters using effect-directed analyses (Doctoral thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:083275

Bačić, Sanja. "Development of fractionation procedures for comprehensive characterization of organic contaminants in surface waters using effect-directed analyses." Doctoral thesis, University of Zagreb, Faculty of Science, 2019. https://urn.nsk.hr/urn:nbn:hr:217:083275

Bačić, Sanja. "Development of fractionation procedures for comprehensive characterization of organic contaminants in surface waters using effect-directed analyses." Doctoral thesis, University of Zagreb, Faculty of Science, 2019. https://urn.nsk.hr/urn:nbn:hr:217:083275

Bačić, S. (2019). 'Development of fractionation procedures for comprehensive characterization of organic contaminants in surface waters using effect-directed analyses', Doctoral thesis, University of Zagreb, Faculty of Science, accessed 28 December 2024, https://urn.nsk.hr/urn:nbn:hr:217:083275

Bačić S. Development of fractionation procedures for comprehensive characterization of organic contaminants in surface waters using effect-directed analyses [Doctoral thesis]. Zagreb: University of Zagreb, Faculty of Science; 2019 [cited 2024 December 28] Available at: https://urn.nsk.hr/urn:nbn:hr:217:083275

S. Bačić, "Development of fractionation procedures for comprehensive characterization of organic contaminants in surface waters using effect-directed analyses", Doctoral thesis, University of Zagreb, Faculty of Science, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:217:083275

Metadata
TitleDevelopment of fractionation procedures for comprehensive characterization of organic contaminants in surface waters using effect-directed analyses
Title (croatian)Razvoj frakcionacijskih postupaka za sveobuhvatnu karakterizaciju organskih zagađivala u površinskim vodama primjenom analiza usmjerenih učincima
AuthorSanja Bačić
MentorMarijan Ahel (mentor)
Committee memberNives Galić (predsjednik povjerenstva)
Committee memberSenka Terzić (član povjerenstva)
Committee memberTvrtko Smital (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Science
(Department of Chemistry)
Zagreb
Defense date and country2019-01-24, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Universal decimal classification
(UDC)		54 - Chemistry. Crystallography. Mineralogy
Abstract
In this work, a novel extraction and fractionation protocol for comprehensive characterization of organic contamination in surface waters using effect-directed analyses (EDA) was developed. A tiered EDA approach was applied, which included a simple EDA protocol, suitable for routine applications, and a higher-tier protocol for a detailed multidimensional fractionation with a final aim to identify key contaminants. A mixed-bed sorbent, consisting of three complementary phases was applied for the extraction, while three different approaches were applied for the fractionation. Sequential elution was found to be the most efficient approach, which provided good recoveries of as well as successful fractionation various organic contaminants according to charge. The developed EDA procedure was successfully applied for the assessment of organic toxicants in the Sava River. Application of a battery of bioassays showed a significant toxicity of Sava River samples, while target and non-target analyses revealed the presence of numerous contaminant classes. The combination of biological and chemical analyses is an important basis for the prioritization of organic contaminants in the Sava River basin.
Abstract (croatian)
U ovom radu razvijeni su ekstrakcijski i frakcionacijski postupci za sveobuhvatnu karakterizaciju organskog onečišćenja u površinskim vodama primjenom analiza usmjerenih učincima (engl. Effect-Directed Analysis, EDA). Prilikom razvoja EDA protokola primijenjen je stupnjeviti pristup koji je uključio razvoj jednostavnog protokola, pogodnog za rutinske analize, te protokola za detaljnu višedimenzionalnu frakcionaciju s ciljem konačne identifikacije kritičnih spojeva. Za ekstrakciju organskih zagađivala upotrijebljena je kombinacija triju sorbensa komplementarnih svojstava, a za frakcionaciju su uspoređena tri različita pristupa. Sekvencijalna eluacija zagađivala s miješanog sorbensa pokazala se najučinkovitijim pristupom jer uz dobra iskorištenja omogućuje i sustavno razdvajanje zagađivala u karakteristične frakcije prema naboju molekule. Razvijeni postupak primijenjen je za ekotoksikološku karakterizaciju zagađivala u rijeci Savi. Primjenom odabranih bioloških testova detektirani su značajni toksični učinci u rijeci Savi, a ciljane i pretražne kemijske analize ukazale prisutnost velikog broja zagađivala. Kombinacija rezultata bioloških i kemijskih analiza predstavlja važnu osnovu za prioritizaciju organskih zagađivala u bazenu rijeke Save.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:217:083275
Study programmeTitle: Doctoral study in chemistry
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor/doktorica znanosti, područje prirodnih znanosti, polje kemija (doktor/doktorica znanosti, područje prirodnih znanosti, polje kemija)
Type of resourceText
Extent237 str. ; 30 cm
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-02-15 13:47:52