prikaz prve stranice dokumenta Genotoksični učinak farmaceutika na školjkaše
  Download
PDF 827.98 KB
undergraduate thesis
Genotoksični učinak farmaceutika na školjkaše
Zagreb: University of Zagreb, Faculty of Science, 2019. urn:nbn:hr:217:516767
Petrina, Petra
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Petrina, P. (2019). Genotoksični učinak farmaceutika na školjkaše (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:516767

Petrina, Petra. "Genotoksični učinak farmaceutika na školjkaše." Undergraduate thesis, University of Zagreb, Faculty of Science, 2019. https://urn.nsk.hr/urn:nbn:hr:217:516767

Petrina, Petra. "Genotoksični učinak farmaceutika na školjkaše." Undergraduate thesis, University of Zagreb, Faculty of Science, 2019. https://urn.nsk.hr/urn:nbn:hr:217:516767

Petrina, P. (2019). 'Genotoksični učinak farmaceutika na školjkaše', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 18 February 2025, https://urn.nsk.hr/urn:nbn:hr:217:516767

Petrina P. Genotoksični učinak farmaceutika na školjkaše [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2019 [cited 2025 February 18] Available at: https://urn.nsk.hr/urn:nbn:hr:217:516767

P. Petrina, "Genotoksični učinak farmaceutika na školjkaše", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:217:516767

Metadata
TitleGenotoksični učinak farmaceutika na školjkaše
Title (english)Genotoxic effects of pharmaceuticals on bivalves
AuthorPetra Petrina
MentorMirjana Pavlica (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2019, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Farmaceutici su raznolika skupina spojeva koji se koriste u svrhu liječenja te prevencije bolesti u ljudi, ali se koriste i u veterini, akvakulturi i stočarstvu. Mjerljive koncentracije ovih spojeva izmjerene su u površinskim vodama diljem svijeta, zbog čega lijekovi i proizvodi za osobnu njegu (PPCP) odnedavno postaju predmetom njihovog istraživanja kao okolišnih zagađivača. Kada se takvi spojevi nađu u okolišu, mogu djelovati na usporedljive biokemijske mehanizme drugih organizama koji nisu bili njihova ciljana meta. Zbog razlika u fiziologiji, ovakvi spojevi mogu biti vrlo toksični za beskralježnjake. U ovom radu obrađen je učinak četiriju često detektiranih farmaceutika u vodenim okolišima, fluoksetina, triklosana, paracetamola i ibuprofena, na školjkaše. Sva četiri spomenuta spoja imaju genotoksični učinak na hemocite školjkaša pri višim koncentracijama. Štetni učinci ovih spojeva mogu se pratiti i pri znatno nižim, okolišnim koncentracijama. Zbog činjenice da farmaceutici opstaju u vodi i nakon njenog pročišćavanja, najugroženije zajednice organizama su upravo one koje žive u blizini postrojenja za obradu otpadnih voda.
Abstract (english)
Pharmaceuticals are a diverse group of chemicals that are used for treating and preventing diseases in people, but are also used in veterinary medicine, aquaculture and agriculture. Measurable concentrations of certain pharmaceuticals have been found in surface waters all over the world, which is why pharmaceuticals and personal care products (PPCSs) are recently being investigated as environmental pollutants. When these chemicals end up in the environment, they can affect comparable pathways of non-target organisms. Due to differences in physiology, these molecules can be highly toxic for invertebrates. In this work, the effect of widely used pharmaceuticals on bivalves was reviewed. All four of mentioned pharmaceuticals, fluoxetine, triclosan, paracetamol and ibuprofen have shown a genotoxic effect on bivalve haemocytes. Harmful effects of these pharmaceuticals can be detected even at environmental concentrations. Due to the persistence of pharmaceuticals after wastewater treatments, the most vulnerable populations of organisms are those living near wastewater treatment plants.
Keywords
Languagecroatian
URN:NBNurn:nbn:hr:217:516767
Study programmeTitle: Environmental Sciences
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) struke znanosti o okolišu (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) struke znanosti o okolišu)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-10-25 07:36:59