prikaz prve stranice dokumenta General theory for the mechanics of confined microtubule asters
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Scientific paper - Original scientific paper
General theory for the mechanics of confined microtubule asters
New Journal of Physics, 16 (2014); 013018-20. https://doi.org/10.1088/1367-2630/16/1/013018
Ma, Rui; Laan, Liedewij; Dogterom, Marileen; Pavin, Nenad; Jülicher, Frank

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Ma, R., Laan, L., Dogterom, M., Pavin, N. & Jülicher, F. (2014). General theory for the mechanics of confined microtubule asters. New Journal of Physics, 16.. doi: 10.1088/1367-2630/16/1/013018

Ma, Rui, et al. "General theory for the mechanics of confined microtubule asters." New Journal of Physics, vol. 16, 2014. https://doi.org/10.1088/1367-2630/16/1/013018

Ma, Rui, Liedewij Laan, Marileen Dogterom, Nenad Pavin and Frank Jülicher. "General theory for the mechanics of confined microtubule asters." New Journal of Physics 16 (2014). https://doi.org/10.1088/1367-2630/16/1/013018

Ma, R., et al. (2014) 'General theory for the mechanics of confined microtubule asters', New Journal of Physics, 16. doi: 10.1088/1367-2630/16/1/013018

Ma R, Laan L, Dogterom M, Pavin N, Jülicher F. General theory for the mechanics of confined microtubule asters. New Journal of Physics [Internet]. 2014 [cited 2024 November 29];16. doi: 10.1088/1367-2630/16/1/013018

R. Ma, L. Laan, M. Dogterom, N. Pavin and F. Jülicher, "General theory for the mechanics of confined microtubule asters", New Journal of Physics, vol. 16, 2014. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:217:454478. [Accessed: 29 November 2024]

Metadata
Title (english)General theory for the mechanics of confined microtubule asters
AuthorRui Ma
AuthorLiedewij Laan
AuthorMarileen Dogterom
AuthorNenad Pavin
AuthorFrank Jülicher
Author's institutionUniversity of Zagreb
Faculty of Science
(Department of Physics)
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Physics
Abstract (english)
In cells, dynamic microtubules organize into asters or spindles to assist positioning of organelles. Two types of forces are suggested to contribute to the positioning process: (i) microtubule-growth based pushing forces ; and (ii) motor protein mediated pulling forces. In this paper, we present a general theory to account for aster positioning in a confinement of arbitrary shape. The theory takes account of microtubule nucleation, growth, catastrophe, slipping, as well as interaction with cortical force generators. We calculate microtubule distributions and forces acting on microtubule organizing centers in a sphere and in an ellipsoid. Positioning mechanisms based on both pushing forces and pulling forces can be distinguished in our theory for different parameter regimes or in different geometries. In addition, we investigate positioning of microtubule asters in the case of asymmetric distribution of motors. This analysis enables us to characterize situations relevant for Caenorrhabditis elegans embryos.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleNew Journal of Physics
Numberingvol. 16, 013018-20
e-ISSN1367-2630
DOIhttps://doi.org/10.1088/1367-2630/16/1/013018
URN:NBNurn:nbn:hr:217:454478
Publication2014
Document URLhttps://iopscience.iop.org/article/10.1088/1367-2630/16/1/013018
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 3.0 Unported (CC BY 3.0) icon
Public note© 2014 IOP Publishing Ltd and Deutsche Physikalische Gesellschaft. Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. Received 27 July 2013; Revised 17 November 2013; Accepted for publication 12 December 2013; Published 15 January 2014.
Created on2019-11-27 22:00:48