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undergraduate thesis
Utjecaj bakteriofaga na patogenost bakterija
Zagreb: University of Zagreb, Faculty of Science, 2019. urn:nbn:hr:217:561442
Puzek, Barbara
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Puzek, B. (2019). Utjecaj bakteriofaga na patogenost bakterija (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:561442

Puzek, Barbara. "Utjecaj bakteriofaga na patogenost bakterija." Undergraduate thesis, University of Zagreb, Faculty of Science, 2019. https://urn.nsk.hr/urn:nbn:hr:217:561442

Puzek, Barbara. "Utjecaj bakteriofaga na patogenost bakterija." Undergraduate thesis, University of Zagreb, Faculty of Science, 2019. https://urn.nsk.hr/urn:nbn:hr:217:561442

Puzek, B. (2019). 'Utjecaj bakteriofaga na patogenost bakterija', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 21 May 2024, https://urn.nsk.hr/urn:nbn:hr:217:561442

Puzek B. Utjecaj bakteriofaga na patogenost bakterija [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2019 [cited 2024 May 21] Available at: https://urn.nsk.hr/urn:nbn:hr:217:561442

B. Puzek, "Utjecaj bakteriofaga na patogenost bakterija", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:217:561442

Metadata
TitleUtjecaj bakteriofaga na patogenost bakterija
Title (english)The impact of bacteriophages on bacterial pathogenicity
AuthorBarbara Puzek
MentorIvana Ivančić Baće (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2019-09-10, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Mogućnost bakterija da uzrokuju bolest (patogenost) često ovisi o bakteriofagima (fagima). Fagi mogu nositi gene za proteine koje, kad se fag ugradi u bakteriju, može sintetizirati stanična mašinerija bakterije i koji joj mogu biti korisni ili čak neophodni u nekom od koraka patogeneze (primanje za domaćina, mijenjanje signalnih puteva i citoskeleta domaćina, preživljavanje imunosnog odgovora). Osim proteinskih produkata kodiranih genima faga, u patogenezi bakterija mogu sudjelovati i cijele čestice faga, modulirajući imunosni odgovor domaćina ili propagirajući nastajanje stabilnih biofilmova. U slučaju bolesti uzrokovanih bakterijama otpornim na antimikrobna sredstva ili bolesti koje se ne mogu kontrolirati antimikrobnim sredstvima, a koje ovise o genima ili česticama faga, fag može biti dobra meta terapije.
Abstract (english)
Bacterial pathogenicity, the ability of bacteria to cause disease, is often dependent on bacteriophages (phages). Phages can carry genes that code for proteins that can be synthetized by the bacterial cell machinery upon integration of the phage into the genome and can be of use or even essential during pathogenesis (for host-adhesion, altering signalling pathways and host cytoskeleton, immune response-survival etc.). As well as phage-encoded-proteins, phage particles can also contribute to pathogenesis, by modulating the immune response or promoting biofilm assembly and stability. Phages can be a good therapy target, in diseases that depend on phage genes or particles, if antimicrobial therapy is not possible due to antimicrobial resistance or the specifics of the disease.
Keywords
Languagecroatian
URN:NBNurn:nbn:hr:217:561442
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-12-02 13:32:37