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master's thesis
Molekulske i kristalne strukture derivata hidroksamske kiseline
Zagreb: University of Zagreb, Faculty of Science, 2019. urn:nbn:hr:217:187867
Veličković, Doris
University of Zagreb
Faculty of Science
Department of Chemistry

Institutional repository: Repository of the Faculty of Science

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Veličković, D. (2019). Molekulske i kristalne strukture derivata hidroksamske kiseline (Master's thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:187867

Veličković, Doris. "Molekulske i kristalne strukture derivata hidroksamske kiseline." Master's thesis, University of Zagreb, Faculty of Science, 2019. https://urn.nsk.hr/urn:nbn:hr:217:187867

Veličković, Doris. "Molekulske i kristalne strukture derivata hidroksamske kiseline." Master's thesis, University of Zagreb, Faculty of Science, 2019. https://urn.nsk.hr/urn:nbn:hr:217:187867

Veličković, D. (2019). 'Molekulske i kristalne strukture derivata hidroksamske kiseline', Master's thesis, University of Zagreb, Faculty of Science, accessed 22 November 2024, https://urn.nsk.hr/urn:nbn:hr:217:187867

Veličković D. Molekulske i kristalne strukture derivata hidroksamske kiseline [Master's thesis]. Zagreb: University of Zagreb, Faculty of Science; 2019 [cited 2024 November 22] Available at: https://urn.nsk.hr/urn:nbn:hr:217:187867

D. Veličković, "Molekulske i kristalne strukture derivata hidroksamske kiseline", Master's thesis, University of Zagreb, Faculty of Science, Zagreb, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:217:187867

Metadata
TitleMolekulske i kristalne strukture derivata hidroksamske kiseline
Title (english)Molecular and crystal structure of hydroxamic acid derivative
AuthorDoris Veličković
MentorIvica Đilović (mentor)
Committee memberIvica Đilović (predsjednik povjerenstva)
Committee memberSanda Rončević (član povjerenstva)
Committee memberVesna Petrović-Peroković (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Science
(Department of Chemistry)
Zagreb
Defense date and country2019-09-30, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Hidroksamske kiseline su slabe organske kiseline koje se rabe u farmaceutskoj industriji, prehrambenoj industriji i metalurgiji. Poznati su kelatori iona metala te se koriste u njihovoj ekstrakciji iz okoline, a u novije vrijeme rabe se u liječenju brojnih bolesti. Cilj ovoga rada bio je sintetizirati novi derivat hidroksamske kiseline i odrediti njegovu molekulsku i kristalnu strukturu. Rendgenskom strukturnom analizom na jediničnom kristalu utvrđeno je da derivat hidroksamske kiseline, N,N',N''-tribenziloksidikarbonimidni diamid kristalizira u triklinskom sustavu te da su u asimetričnoj jedinici pronađene dvije simetrijski neovisne molekule slične konformacije. Duljine veza i valentni kutevi u skladu su s već opaženima za slične spojeve. Karakteristično za priređeni spoj jest da njegove molekule posjeduju unutarmolekulsku vodikovu vezu koja „zaključava“ konformaciju središnjeg dijela molekule, tj. čini ga planarnim. U kristalnoj strukturi, molekule su povezane u centrosimetrične dimere koji su vodikovim i slabijim interakcijama povezani u lance.
Abstract (english)
Hydroxamic acids are weak organic acids that are used in the pharmaceutical or food industries and metallurgy. They are known as good metal ion chelators which is particulary useful in extraction from the environment or in the treatment of many diseases. The aim of this study was to synthesize a new hydroxamic acid derivative and to determine its molecular and crystal structure. X-ray structural analysis on a single crystal revealed that the hydroxamic acid derivative, namely, N, N',N''- tribenzyloxydicarbonimide diamide crystallizes in the triclinic system with two symmetrically independent molecules (of similar conformation) in the asymmetric unit. The bond lengths and valence angles are comparable to those found in the literature. Characteristic of the prepared compound is that its molecules have an intramolecular hydrogen bond that "locks" the conformation of the central part of the molecule, i.e., makes it planar. In the crystal structure, the molecules are linked into centrosymmetric dimers that are linked into chains by hydrogen and weak interactions.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:187867
Study programmeTitle: Chemistry
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra kemije (magistar/magistra kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Embargo expiration date: 2020-09-30
Terms of useLicence In copyright icon
Created on2020-01-10 13:33:37