prikaz prve stranice dokumenta Utjecaj satelitne DNA na regulaciju gena u brašnara Tribolium castaneum (Herbst 1797)
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master's thesis
Utjecaj satelitne DNA na regulaciju gena u brašnara Tribolium castaneum (Herbst 1797)
Zagreb: University of Zagreb, Faculty of Science, 2013. urn:nbn:hr:217:628381
Akrap, Ivana
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

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Akrap, I. (2013). Utjecaj satelitne DNA na regulaciju gena u brašnara Tribolium castaneum (Herbst 1797) (Master's thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:628381

Akrap, Ivana. "Utjecaj satelitne DNA na regulaciju gena u brašnara Tribolium castaneum (Herbst 1797)." Master's thesis, University of Zagreb, Faculty of Science, 2013. https://urn.nsk.hr/urn:nbn:hr:217:628381

Akrap, Ivana. "Utjecaj satelitne DNA na regulaciju gena u brašnara Tribolium castaneum (Herbst 1797)." Master's thesis, University of Zagreb, Faculty of Science, 2013. https://urn.nsk.hr/urn:nbn:hr:217:628381

Akrap, I. (2013). 'Utjecaj satelitne DNA na regulaciju gena u brašnara Tribolium castaneum (Herbst 1797)', Master's thesis, University of Zagreb, Faculty of Science, accessed 22 November 2024, https://urn.nsk.hr/urn:nbn:hr:217:628381

Akrap I. Utjecaj satelitne DNA na regulaciju gena u brašnara Tribolium castaneum (Herbst 1797) [Master's thesis]. Zagreb: University of Zagreb, Faculty of Science; 2013 [cited 2024 November 22] Available at: https://urn.nsk.hr/urn:nbn:hr:217:628381

I. Akrap, "Utjecaj satelitne DNA na regulaciju gena u brašnara Tribolium castaneum (Herbst 1797)", Master's thesis, University of Zagreb, Faculty of Science, Zagreb, 2013. Available at: https://urn.nsk.hr/urn:nbn:hr:217:628381

Metadata
TitleUtjecaj satelitne DNA na regulaciju gena u brašnara Tribolium castaneum (Herbst 1797)
Title (english)Study of satellite DNA-mediated gene regulation in red flour beetle Tribolium castaneum (Herbst, 1797)
AuthorIvana Akrap
MentorĐurđica Ugarković (mentor)
Committee memberVlatka Zoldoš (predsjednik povjerenstva)
Committee memberĐurđica Ugarković (član povjerenstva)
Committee memberMirjana Kalafatić (član povjerenstva)
Committee memberDijana Škorić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2013-02-11, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Satelitne DNA predstavljaju uzastopno ponavljajuće sekvence koje čine značajan dio genoma eukariotskih organizama. Glavni su građevni elementi pericentromernog i centromernog hetrokromatina. Njihove strukturne odlike, očuvani motivi i transkripcijska aktivnost upućuju također na njihovu ulogu u regulaciji ekspresije gena. TCAST predstavlja glavnu satelitnu DNA u brašnara Tribolium castaneum. Raspršeni oblik TCAST-a je pronađen u blizini velikog broja (101) unikatnog gena. U ovome radu otkriven je polimorfizam raspršenog satelita TCAST među sojevima brašnara T. castaneum i kao mogući mehanizam raspršenja satelita predložena je mjesno-specifična rekombinacija. Dobiveni rezultati također upućuju na moguću ulogu raspršenog satelita TCAST u regulaciji gena koji se nalaze u njegovoj blizini, u uvjetima temperaturnog stresa.
Abstract (english)
Satellite DNAs are tandemly repeated sequences that constitute a considerable part of the genomic DNA of many eukaryotic organisms. They represent a major building element of pericentromeric and centromeric heterochromatin. The existence of conserved motifs and structural properties and their transcriptional activity suggest that, in addition to participating in centromere and heterochromatin formation, satellite DNAs might also act as cis-regulatory elements of gene expression. TCAST represents major satellite DNA in the red flour beetle Tribolium castaneum. Dispersed form of TCAST satellite was associated with 101 proteincoding genes. This study reveals polymorphism of dispersed TCAST satellite-like elements among strains of T. castaneum and gives a strong indication for the role of site specific recombination as a mechanism of dispersion of repetitive elements. The results of this study also suggest the role of dispersed TCAST satellite-like elements in regulation of genes located in their vicinity, under specific heat stress conditions.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:628381
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra molekularne biologije (magistar/magistra molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-04-25 10:35:08