prikaz prve stranice dokumenta Bridging the gap between sister kinetochores
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Scientific paper - Other
Bridging the gap between sister kinetochores
Cell cycle, 15 (2016), 9; 1169-1170. https://doi.org/10.1080/15384101.2016.1157976
Tolić, Iva Marija; Pavin, Nenad

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Tolić, I. M. & Pavin, N. (2016). Bridging the gap between sister kinetochores. Cell cycle, 15. (9), 1169-1170. doi: 10.1080/15384101.2016.1157976

Tolić, Iva Marija and Nenad Pavin. "Bridging the gap between sister kinetochores." Cell cycle, vol. 15, no. 9, 2016, pp. 1169-1170. https://doi.org/10.1080/15384101.2016.1157976

Tolić, Iva Marija and Nenad Pavin. "Bridging the gap between sister kinetochores." Cell cycle 15, no. 9 (2016): 1169-1170. https://doi.org/10.1080/15384101.2016.1157976

Tolić, I. M. and Pavin, N. (2016) 'Bridging the gap between sister kinetochores', Cell cycle, 15(9), pp. 1169-1170. doi: 10.1080/15384101.2016.1157976

Tolić IM, Pavin N. Bridging the gap between sister kinetochores. Cell cycle [Internet]. 2016 [cited 2024 November 24];15(9):1169-1170. doi: 10.1080/15384101.2016.1157976

I. M. Tolić and N. Pavin, "Bridging the gap between sister kinetochores", Cell cycle, vol. 15, no. 9, pp. 1169-1170, 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:217:182118. [Accessed: 24 November 2024]

Metadata
Title (english)Bridging the gap between sister kinetochores
AuthorIva Marija Tolić
MBZ: 260543
AuthorNenad Pavin
MBZ: 204800
Author's institutionUniversity of Zagreb
Faculty of Science
(Department of Physics)
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Physics
Abstract (english)
The main task of the mitotic spindle is to generate forces that position the chromosomes at the metaphase plate and subsequently pull them apart toward the opposite spindle poles. These forces in living cells are, unfortunately, not easily accessible by current experimental techniques. However, much about the forces can be inferred from the shape of the spindle because the shape is an outcome of forces. K-fibers, which are bundles of microtubules ending at the kinetochore, are typically curved, suggesting that they are under compression. By severing a k-fiber with a laser we have shown that the bridging fiber moves together with sister k-fibers, revealing that these 3 fibers are strongly linked and thus able to survive large physical perturbations such as cutting of k-fibers. Severing of a k-fiber at different locations also revealed that the bridging fiber is linked laterally to the k-fibers in the region away from the kinetochore, while these fibers separate from each other close to the kinetochore.
Keywords (english)
Languageenglish
Publication typeScientific paper - Other
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCell cycle
Numberingvol. 15, no. 9, pp. 1169-1170
p-ISSN1538-4101
DOIhttps://doi.org/10.1080/15384101.2016.1157976
URN:NBNurn:nbn:hr:217:182118
Publication2016
Document URLhttps://www.tandfonline.com/doi/full/10.1080/15384101.2016.1157976
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0) icon
Public note© 2016 Iva M. Tolić and Nenad Pavin. Published with license by Taylor and Francis. This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted. Received 8 February 2016. Accepted 22 February 2016. Published online: 25 Apr 2016.
Created on2020-02-23 14:22:11