prikaz prve stranice dokumenta Priprava i studij vezivanja permetiliranih diamantoidnih amonijevih soli s ciklodekstrinima
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master's thesis
Priprava i studij vezivanja permetiliranih diamantoidnih amonijevih soli s ciklodekstrinima
Zagreb: University of Zagreb, Faculty of Science, 2020. urn:nbn:hr:217:198573
Jozepović, Ruža
University of Zagreb
Faculty of Science
Department of Chemistry

Institutional repository: Repository of the Faculty of Science

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Jozepović, R. (2020). Priprava i studij vezivanja permetiliranih diamantoidnih amonijevih soli s ciklodekstrinima (Master's thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:198573

Jozepović, Ruža. "Priprava i studij vezivanja permetiliranih diamantoidnih amonijevih soli s ciklodekstrinima." Master's thesis, University of Zagreb, Faculty of Science, 2020. https://urn.nsk.hr/urn:nbn:hr:217:198573

Jozepović, Ruža. "Priprava i studij vezivanja permetiliranih diamantoidnih amonijevih soli s ciklodekstrinima." Master's thesis, University of Zagreb, Faculty of Science, 2020. https://urn.nsk.hr/urn:nbn:hr:217:198573

Jozepović, R. (2020). 'Priprava i studij vezivanja permetiliranih diamantoidnih amonijevih soli s ciklodekstrinima', Master's thesis, University of Zagreb, Faculty of Science, accessed 21 December 2024, https://urn.nsk.hr/urn:nbn:hr:217:198573

Jozepović R. Priprava i studij vezivanja permetiliranih diamantoidnih amonijevih soli s ciklodekstrinima [Master's thesis]. Zagreb: University of Zagreb, Faculty of Science; 2020 [cited 2024 December 21] Available at: https://urn.nsk.hr/urn:nbn:hr:217:198573

R. Jozepović, "Priprava i studij vezivanja permetiliranih diamantoidnih amonijevih soli s ciklodekstrinima", Master's thesis, University of Zagreb, Faculty of Science, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:217:198573

Metadata
TitlePriprava i studij vezivanja permetiliranih diamantoidnih amonijevih soli s ciklodekstrinima
Title (english)Synthesis and binding study of permathylated diamondoid ammonium salts with cyclodextrines
AuthorRuža Jozepović
MentorMarija Alešković (mentor)
Committee memberĐani Škalamera (predsjednik povjerenstva)
Committee memberIva Juranović Cindrić (član povjerenstva)
Committee memberNikola Bregović (član povjerenstva)
Committee memberNikola Cindro (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Science
(Department of Chemistry)
Zagreb
Defense date and country2020-09-30, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
U okviru ovog rada provedena je sinteza N,N,N-trimetiladamantan-1-amonijevog jodida (1), N,N,N-trimetildiamantan-4-amonijevog jodida (2) i N,N,N,N',N',N'-heksametildiamantan-4,9- diamonijevog dijodida (3). Amonijeva sol 1 pripravljena je permetiliranjem komercijalno dostupnog 1-aminoadamantana dok su spojevi 2 i 3 sintetizirani slijedom reakcija počevši od diamantanskog ugljikovodika. Svi pripravljeni spojevi okarakterizirani su uobičajenim analitičkim tehnikama, a ciljne molekule 1–3 zatim su ispitivane kao molekule gosti kod kompleksiranja s β- i γ-ciklodekstrinima u vodenim otopinama. Studij vezivanja molekula 1–3 s β- i γ-ciklodekstrinima proveden je titracijskim 1H NMR eksperimentima u D2O otopinama te se temeljem dobivenih rezultata zaključuje da nastaju kompleksi između β-ciklodekstrina i gosta 1 odnosno 2 te γ-ciklodekstrina i gosta 2. Svi navedeni kompleksi su 1:1 stehiometrije uz vrijednosti konstanti stabilnosti ≥ 103 mol–1 dm3.
Abstract (english)
In the scope of this work synthesis of N,N,N-trimethyladamantane-1-ammonium iodide (1), N,N,N-trimethyldiamantane-4-ammonium iodide (2) and N,N,N,N',N',N'-hexamethyldiamantane- 4,9-diammonium diiodide (3) was performed. Ammonium salt 1 was prepared by permethylation of commercially available 1-aminoadamantane while compounds 2 and 3 were prepared through a series of reactions starting from the diamantane hydrocarbon. All synthesized compounds were characterized by usual analytical techniques and target molecules 1–3 were then tested as guest molecules in complexation with β- and γ-cyclodextrins in aqueous solutions. Binding studies of molecules 1–3 with β- and γ-cyclodextrins were performed using 1H NMR titration experiments in D2O solutions and the obtained results demonstrated that complexes of β- cyclodextrin and guests 1 or 2, respectively and γ-cyclodextrin and guest 2 were formed. All the observed complexes were of a 1:1 stoichiometry with the values of stability constants ≥ 103 mol–1 dm3.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:198573
Study programmeTitle: Graduate university studies in chemistry; specializations in: Research programme
Course: Research programme
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra kemije (magistar/magistra kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Embargo expiration date: 2022-10-01
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Created on2020-10-16 09:56:46