prikaz prve stranice dokumenta Primjena proteomske analize u identifikaciji biomarkera karcinoma prostate
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master's thesis
Primjena proteomske analize u identifikaciji biomarkera karcinoma prostate
Zagreb: University of Zagreb, Faculty of Science, 2013. urn:nbn:hr:217:703069
Skenderović, Anamarija
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Skenderović, A. (2013). Primjena proteomske analize u identifikaciji biomarkera karcinoma prostate (Master's thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:703069

Skenderović, Anamarija. "Primjena proteomske analize u identifikaciji biomarkera karcinoma prostate." Master's thesis, University of Zagreb, Faculty of Science, 2013. https://urn.nsk.hr/urn:nbn:hr:217:703069

Skenderović, Anamarija. "Primjena proteomske analize u identifikaciji biomarkera karcinoma prostate." Master's thesis, University of Zagreb, Faculty of Science, 2013. https://urn.nsk.hr/urn:nbn:hr:217:703069

Skenderović, A. (2013). 'Primjena proteomske analize u identifikaciji biomarkera karcinoma prostate', Master's thesis, University of Zagreb, Faculty of Science, accessed 22 November 2024, https://urn.nsk.hr/urn:nbn:hr:217:703069

Skenderović A. Primjena proteomske analize u identifikaciji biomarkera karcinoma prostate [Master's thesis]. Zagreb: University of Zagreb, Faculty of Science; 2013 [cited 2024 November 22] Available at: https://urn.nsk.hr/urn:nbn:hr:217:703069

A. Skenderović, "Primjena proteomske analize u identifikaciji biomarkera karcinoma prostate", Master's thesis, University of Zagreb, Faculty of Science, Zagreb, 2013. Available at: https://urn.nsk.hr/urn:nbn:hr:217:703069

Metadata
TitlePrimjena proteomske analize u identifikaciji biomarkera karcinoma prostate
Title (english)Application of proteomic analysis in the identification of prostate carcinoma biomarkers
AuthorAnamarija Skenderović
MentorMario Cindrić (mentor)
Committee memberMario Cindrić (predsjednik povjerenstva)
Committee memberVesna Benković (član povjerenstva)
Committee memberMirna Ćurković Perica (član povjerenstva)
Committee memberInga Marijanović (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2013-02-15, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Proteomska tehnologija u istraživanju tumorskih bolesti koristi se u detekciji ranih stadija bolesti, određivanju stadija i progresije bolesti, otkrivanja potencijalnih meta i biomarkera za liječenje bolesti te u konačnici za primjenu terapije prilagođene svakom individualnom pacijentu na osnovu njegovog proteomskog profila. Tumor prostate jedno je od najčešće dijagnosticiranih malignih oboljenja muškaraca nakon pedesete godine života. U ovom radu primijenjen je proteomski pristup za utvrđivanje razlikovnog prikaza oboljenja karcinoma prostate, a u svrhu pronalaska potencijalnih novih biomarkera za bolju procjenu progresije i agresivnosti bolesti. Nakon histopatološkog nalaza, proteini tumorom zaraženog i zdravog tkiva prostate identificirani su dvodimenzionalnom gel elektroforezom u sprezi sa spektrometrijom masa. Dobiveni rezultati i razvijena metodologija čine okosnicu za daljnja istraživanja na većem broju uzoraka.
Abstract (english)
Proteomics technology in the research of tumor diseases is used in detection of early stages of disease development, tumor staging and progression, identification of potential targets and biomarkers. Collected proteomics data could direct disease treatment and could have impact on administrated therapy adjusted for every individual patient based on his proteomics profile. Prostate tumor is one of the leading diagnosed malignant disease of men after the age of 50. Proteomics methodology applied in the thesis utilitized for an observation of differential display of prostate tumor disease vs. health disease. Final goal was identification of potential novel biomarkers for better understanding of disease progression and agression. After histopathological determination, proteins from tumor-infected and health prostate tissue were separated by two-dimensional gel electrophoresis followed by mass spectrometry identification. Presented results and methodology can be used as basis for following population researches.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:703069
Study programmeTitle: Molecular Biology
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra molekularne biologije (magistar/magistra molekularne biologije)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2017-04-28 08:10:08