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undergraduate thesis
Imunohistokemijske metode u dijagnostici i istraživanju infektivnih bolesti
Zagreb: University of Zagreb, Faculty of Science, 2021. urn:nbn:hr:217:676905
Dupanović, Alma
University of Zagreb
Faculty of Science
Department of Biology

Institutional repository: Repository of the Faculty of Science

Cite this document

Dupanović, A. (2021). Imunohistokemijske metode u dijagnostici i istraživanju infektivnih bolesti (Undergraduate thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:676905

Dupanović, Alma. "Imunohistokemijske metode u dijagnostici i istraživanju infektivnih bolesti." Undergraduate thesis, University of Zagreb, Faculty of Science, 2021. https://urn.nsk.hr/urn:nbn:hr:217:676905

Dupanović, Alma. "Imunohistokemijske metode u dijagnostici i istraživanju infektivnih bolesti." Undergraduate thesis, University of Zagreb, Faculty of Science, 2021. https://urn.nsk.hr/urn:nbn:hr:217:676905

Dupanović, A. (2021). 'Imunohistokemijske metode u dijagnostici i istraživanju infektivnih bolesti', Undergraduate thesis, University of Zagreb, Faculty of Science, accessed 04 November 2024, https://urn.nsk.hr/urn:nbn:hr:217:676905

Dupanović A. Imunohistokemijske metode u dijagnostici i istraživanju infektivnih bolesti [Undergraduate thesis]. Zagreb: University of Zagreb, Faculty of Science; 2021 [cited 2024 November 04] Available at: https://urn.nsk.hr/urn:nbn:hr:217:676905

A. Dupanović, "Imunohistokemijske metode u dijagnostici i istraživanju infektivnih bolesti", Undergraduate thesis, University of Zagreb, Faculty of Science, Zagreb, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:217:676905

Metadata
TitleImunohistokemijske metode u dijagnostici i istraživanju infektivnih bolesti
Title (english)Application of immunohistochemistry in diagnostics and research of infectious diseases
AuthorAlma Dupanović
MentorRomana Gračan (mentor)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2021, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Imunohistokemijske metode omogućavaju vizualizaciju raznih antigena u tkivu koristeći se njima specifičnim protutijelima. Premda se počela razvijati prije više od 80 godina, imunohistokemija je i danas često korištena u mnoge svrhe: ključna je za dijagnostiku i praćenje određenih tumora te istraživanje neurodegenerativnih bolesti koje su sve češći problem današnjice, a osim toga značajna je i u dijagnostici i istraživanju raznih infektivnih bolesti. Imunohistokemijske metode pružaju jedinstven uvid u distribuciju antigena u tkivu, što pomaže u istraživanju patogeneze raznih bolesti koje izazivaju mikroorganizmi. Postupci imunohistokemijskog bojenja sastoje se od više koraka koji imaju značajan utjecaj na krajnji rezultat te je upravo ovo jedan od razloga zašto su brze i jednostavne molekularne i serološke metode preuzele prednost u dijagnostici zaraznih bolesti. Međutim, na brojnim primjerima dokazano je da je imunohistokemija, bez obzira na nedostatke, snažan i vrijedan alat u istraživanjima bolesti, osobito u kombinaciji s drugim metodama, poput in situ hibridizacije.
Abstract (english)
Immunohistochemistry enables visualisation of various antigens in tissues with the help of specific antibodies. Although immunohistochemistry has been around for 80 years, it is still often used for many purposes: it is key in diagnosis and surveillance of certain tumors, as well as research of neurodegenerative diseases which have become an increasingly common problem, but are also important in diagnosis and research of different infectious diseases. Immunohistochemistry provides a unique insight in distribution of antigens in tissues, which is of great assistance in research of pathogenesis of different diseases caused by microorganisms. The process of immunohistochemical staining consists of several steps that have a significant impact on the end result, which is one of the reasons why fast and simple molecular and serological methods have an advantage in diagnosis of infectious diseases. However, even with its flaws, many examples of application of immunohistochemistry prove that, it is a very powerful and valuable tool in research, especially when combined with other methods, like in situ hybridisation.
Keywords
Languagecroatian
URN:NBNurn:nbn:hr:217:676905
Study programmeTitle: Ecology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-09-03 06:47:01