Burnout among students has become a more common topic among researchers, but it is still a relatively new and poorly researched theme. Academic burnout is an significant psychological problem among students which leads to emotional, physical and cognitive exhaustion and sense of alienation. Numerous studies show that about half of students show symptoms of burnout or that they are in risk of burnout. Accordingly, it is important to determine the prevalence of burnout among students and to identify the characteristics that contribute to it. The theoretical framework of this study was Lazarus' model of stress, while the aim of the research was to examine determinants of academic burnout among students of the University of Zagreb in the context of socio-demographic characteristics and study characteristics. The study was conducted as web survey on a sample of 764 students from different faculties at University of Zagreb. The results have shown that there is no statistically significant differences between male and female students in academic burnout, that older students achieved higher scores on both dimensions of burnout, and that there is a negative correlation between study satisfaction, satisfaction with academic success and academic burnout. The results indicate a need to develop interventions aimed at the prevention of academic burnout in the student population. Keywords: academic burnout, Lazarus' model of stress, mental health, students of the University of Zagreb