The topic of this paper is human resources management in health care in the Republic of Croatia. As the human resources department is very important in every organization, including healthcare, which is very large and complex, its management is more important than anything because everything starts from it. The first half of the paper explains in general the management of human resources in the organization of concepts to business of human resources. The following is a general explanation of the method of employment in the public service of the Republic of Croatia. Development of official legislation in the Republic of Croatia on the manner of employment, elections and the possibility of rewards of employees. There are also explanations and additional measures to improve human resource management at the organizational, normative, personal and technical levels. The second half of the paper talks about human resources management in the health of the Republic of Croatia and this is also the topic of this paper. In this part of the explanation, the most important terms that enter the system of human resources from planning, external influences (factors), programs, evaluation, development, recruitment and selection, hiring new employees, work organization and planning process in the hospital. Finally, we looked at quality and standard management, which are also an important link in every healthcare institution.