Disability represents the relationship between a person who has certain impairments and his environment. It is in this relationship that the attitudes of that environment play a big role. The aim of this research was to examine the attitudes of the citizens of the city of Sisak towards persons with disabilities, and the differences in attitudes regarding age, gender, educational status, size of place of residence, marital status of respondents, estimated knowledge about persons with disabilities and acquaintance with a person with disabilities were examined. The web survey method was used, and 201 adult participants took part in the research. The results of this research showed the existence of a statistically significant difference in the attitudes towards people with disabilities with regard to the age of the respondents, where people in the age groups of 18 to 29 years and 56 to 65 years express more negative attitudes. Despite numerous studies, there were no differences in the attitudes towards people with disabilities with regard to the sex of the respondents, the size of the respondents' place of residence, as well as the marital status of the respondents. People with a higher level of education expressed more positive attitudes towards people with disabilities. Respondents who assess their knowledge of persons with disabilities as extremely poor or bad expressed more negative attitudes towards persons with disabilities, and the same was true of respondents who do not know a person with disabilities. This research showed that among the citizens of the city of Sisak there are negative attitudes towards people with disabilities and that certain groups are more susceptible to them, which is in line with part of the existing literature.